RCAN1

RCAN1
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1WEY
Dynodwyr
Cyfenwau	RCAN1, ADAPT78, CSP1, DSC1, DSCR1, MCIP1, RCN1, regulator of calcineurin 1
Dynodwyr allanol	OMIM: 602917 HomoloGene: 3251 GeneCards: RCAN1
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • GO:0001131, GO:0001151, GO:0001130, GO:0001204 DNA-binding transcription factor activity • DNA binding • GO:0001948, GO:0016582 protein binding • calcium-dependent protein serine/threonine phosphatase regulator activity • identical protein binding • nucleic acid binding Cydrannau o'r gell • cytoplasm • cnewyllyn cell Prosesau biolegol • regulation of calcineurin-NFAT signaling cascade • central nervous system development • calcineurin-NFAT signaling cascade • blood circulation • GO:0072468 signal transduction • calcium-mediated signaling • GO:0009373 regulation of transcription, DNA-templated • regulation of phosphoprotein phosphatase activity • negative regulation of calcineurin-NFAT signaling cascade Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	1827	n/a
Ensembl	ENSG00000159200	n/a
UniProt	P53805	n/a
RefSeq (mRNA)	NM_001285389 NM_001285391 NM_001285392 NM_001285393 NM_004414 NM_203417 NM_203418 NM_001331016	n/a
RefSeq (protein)	NP_001272318 NP_001272320 NP_001272321 NP_001272322 NP_001317945 NP_004405 NP_981962 NP_981963	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn RCAN1 yw RCAN1 a elwir hefyd yn Regulator of calcineurin 1 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 21, band 21q22.12.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn RCAN1.

• CSP1
• DSC1
• RCN1
• DSCR1
• MCIP1
• ADAPT78

Llyfryddiaeth

• "The effect of RCAN1 on the biological behaviors of small cell lung cancer. ". Tumour Biol. 2017. PMID 28631570.
• "Regulator of Calcineurin 1 Gene Isoform 4, Down-regulated in Hepatocellular Carcinoma, Prevents Proliferation, Migration, and Invasive Activity of Cancer Cells and Metastasis of Orthotopic Tumors by Inhibiting Nuclear Translocation of NFAT1. ". Gastroenterology. 2017. PMID 28583823.
• "The regulator of calcineurin 1 (RCAN1) inhibits nuclear factor kappaB signaling pathway and suppresses human malignant glioma cells growth. ". Oncotarget. 2017. PMID 28061453.
• "Down syndrome critical region 1 positively correlates with angiogenesis in hypopharyngeal cancer. ". Mol Med Rep. 2017. PMID 27922696.
• "The regulator of calcineurin 1 increases adenine nucleotide translocator 1 and leads to mitochondrial dysfunctions.". J Neurochem. 2017. PMID 27861892.