RBM14

RBM14
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2DNP
Dynodwyr
Cyfenwau	RBM14, COAA, PSP2, SIP, SYTIP1, TMEM137, RNA binding motif protein 14
Dynodwyr allanol	OMIM: 612409 HomoloGene: 4614 GeneCards: RBM14
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • GO:0001948, GO:0016582 protein binding • protein-macromolecule adaptor activity • GO:0001104 transcription coregulator activity • nuclear receptor coactivator activity • nucleic acid binding • RNA binding Cydrannau o'r gell • nucleolus • mediator complex • transcription regulator complex • cytoplasm • cnewyllyn cell • nuclear speck • nucleoplasm • ribonucleoprotein complex Prosesau biolegol • glucocorticoid receptor signaling pathway • response to hormone • SMAD protein signal transduction • DNA recombination • GO:0100026 DNA repair • GO:0009373 regulation of transcription, DNA-templated • DNA replication • intracellular estrogen receptor signaling pathway • transcription, DNA-templated • negative regulation of centriole replication • histone deacetylation • GO:0003257, GO:0010735, GO:1901228, GO:1900622, GO:1904488 positive regulation of transcription by RNA polymerase II • centriole assembly • activation of innate immune response • immune system process • innate immune response Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	10432	n/a
Ensembl	ENSG00000239306	n/a
UniProt	Q96PK6	n/a
RefSeq (mRNA)	NM_032886 NM_001198836 NM_001198837 NM_006328	n/a
RefSeq (protein)	NP_001185765 NP_001185766 NP_006319	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn RBM14 yw RBM14 a elwir hefyd yn RNA binding motif protein 14 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 11, band 11q13.2.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn RBM14.

• SIP
• COAA
• PSP2
• SYTIP1
• TMEM137

Llyfryddiaeth

• "Switched alternative splicing of oncogene CoAA during embryonal carcinoma stem cell differentiation. ". Nucleic Acids Res. 2007. PMID 17337438.
• "Gene amplification and associated loss of 5' regulatory sequences of CoAA in human cancers. ". Oncogene. 2007. PMID 16878147.
• "Prion-like domains in RNA binding proteins are essential for building subnuclear paraspeckles. ". J Cell Biol. 2015. PMID 26283796.
• "RNA binding protein RBM14 promotes radio-resistance in glioblastoma by regulating DNA repair and cell differentiation. ". Oncotarget. 2014. PMID 24811242.
• "Dual roles for coactivator activator and its counterbalancing isoform coactivator modulator in human kidney cell tumorigenesis.". Cancer Res. 2008. PMID 18829545.