RBBP6

RBBP6
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2C7H, 2YSA, 2YUR, 3ZTG
Dynodwyr
Cyfenwau	RBBP6, MY038, P2P-R, PACT, RBQ-1, SNAMA, retinoblastoma binding protein 6, RB binding protein 6, ubiquitin ligase
Dynodwyr allanol	OMIM: 600938 HomoloGene: 136812 GeneCards: RBBP6
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • GO:0001948, GO:0016582 protein binding • zinc ion binding • nucleic acid binding • metal ion binding • GO:0050372 ubiquitin-protein transferase activity • GO:1904264, GO:1904822, GO:0090622, GO:0090302 ubiquitin protein ligase activity • transferase activity • RNA binding • protein kinase binding Cydrannau o'r gell • nucleolus • microtubule organizing center • cnewyllyn cell • Cromosom • cytoplasm • Cytosgerbwd • cytosol • centrosome • nuclear speck • GO:0009327 protein-containing complex Prosesau biolegol • in utero embryonic development • embryonic organ development • regulation of DNA replication • DNA replication • cellular response to DNA damage stimulus • protein ubiquitination • multicellular organism growth • somite development • mRNA processing • protein polyubiquitination • ubiquitin-dependent protein catabolic process Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	5930	n/a
Ensembl	ENSG00000122257	n/a
UniProt	Q7Z6E9	n/a
RefSeq (mRNA)	NM_006910 NM_018703 NM_032626	n/a
RefSeq (protein)	NP_008841 NP_061173 NP_116015	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn RBBP6 yw RBBP6 a elwir hefyd yn E3 ubiquitin-protein ligase RBBP6 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 16, band 16p12.1.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn RBBP6.

• PACT
• MY038
• P2P-R
• RBQ-1
• SNAMA

Llyfryddiaeth

• "Association of genetic variants in the retinoblastoma binding protein 6 gene with the risk of glioma: a case-control study in a Chinese Han population. ". J Neurosurg. 2014. PMID 25127414.
• "Silencing RBBP6 (Retinoblastoma Binding Protein 6) sensitises breast cancer cells MCF7 to staurosporine and camptothecin-induced cell death. ". Immunobiology. 2014. PMID 24703106.
• "Expression analysis and association of RBBP6 with apoptosis in colon cancers. ". J Mol Histol. 2016. PMID 26905308.
• "Germline RBBP6 mutations in familial myeloproliferative neoplasms. ". Blood. 2016. PMID 26574608.
• "The association of RBBP6 variant 3 expressions with apoptosis in human immunodeficiency virus-associated nephropathy (HIVAN).". Exp Mol Pathol. 2015. PMID 25910411.