RARA

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RARA
Protein RARA PDB 1dkf.png
Strwythurau
PDBOrthologau:PDBe RCSB
Dynodwyr
CyfenwauRARA, NR1B1, RAR, retinoic acid receptor alpha
Dynodwyr allanolOMIM: 180240 MGI: 97856 HomoloGene: 20262 GeneCards: RARA
Patrwm RNA pattern
PBB GE RARA 203750 s at fs.png

PBB GE RARA 211605 s at fs.png

PBB GE RARA 203749 s at fs.png
Rhagor o gyfeiriadau
Orthologau
SpeciesBod dynolLlygoden
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_000964
NM_001024809
NM_001033603
NM_001145301
NM_001145302

NM_001176528
NM_001177302
NM_001177303
NM_009024
NM_001361954

RefSeq (protein)

NP_001169999
NP_001170773
NP_001170774
NP_033050
NP_001348883

Lleoliad (UCSC)n/aChr : 98.93 – 98.97 Mb
PubMed search[2][3]
Wicidata
Gweld/Golygu Bod dynolGweld/Golygu Llygoden

Protein sy'n cael ei godio yn y corff dynol gan y genyn RARA yw RARA a elwir hefyd yn RARA protein (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 17, band 17q21.2.[4]

Cyfystyron[golygu | golygu cod y dudalen]

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn RARA.

  • RAR
  • NR1B1

Llyfryddiaeth[golygu | golygu cod y dudalen]

  • "Enhanced expression of retinoic acid receptor alpha (RARA) induces epithelial-to-mesenchymal transition and disruption of mammary acinar structures. ". Mol Oncol. 2015. PMID 25300573.
  • "Expression and Subcellular Localization of Retinoic Acid Receptor-α (RARα) in Healthy and Varicocele Human Spermatozoa: Its Possible Regulatory Role in Capacitation and Survival. ". Appl Immunohistochem Mol Morphol. 2015. PMID 24992177.
  • "NLS‑RARα modulates acute promyelocytic leukemia NB4 cell proliferation and differentiation via the PI3K/AKT pathway. ". Mol Med Rep. 2016. PMID 27840989.
  • "RARα mediates all-trans-retinoic acid-induced VEGF-C, VEGF-D, and VEGFR3 expression in lung cancer cells. ". Cell Biol Int. 2016. PMID 26818829.
  • "All-trans retinoic acid synergizes with topotecan to suppress AML cells via promoting RARα-mediated DNA damage.". BMC Cancer. 2016. PMID 26728137.

Cyfeiriadau[golygu | golygu cod y dudalen]

  1. 1.0 1.1 1.2 GRCm38: Ensembl release 89: ENSMUSG00000037992 - Ensembl, May 2017
  2. "Human PubMed Reference:".
  3. "Mouse PubMed Reference:".
  4. RARA - Cronfa NCBI