RAP1GAP

RAP1GAP
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1SRQ, 3BRW
Dynodwyr
Cyfenwau	RAP1GAP, RAP1GA1, RAP1GAP1, RAP1GAPII, RAPGAP, RAP1 GTPase activating protein
Dynodwyr allanol	OMIM: 600278 HomoloGene: 2163 GeneCards: RAP1GAP
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • protein homodimerization activity • GO:0005083 GTPase regulator activity • GO:0001948, GO:0016582 protein binding • GO:0006184 GTPase activity • GO:0005097, GO:0005099, GO:0005100 GTPase activator activity Cydrannau o'r gell • Golgi apparatus • bilen • Golgi membrane • cytosol Prosesau biolegol • negative regulation of microvillus assembly • GO:0043087, GO:0032313, GO:0032319, GO:0032314, GO:0043088 regulation of GTPase activity • GO:0032320, GO:0032321, GO:0032855, GO:0043089, GO:0032854 positive regulation of GTPase activity • regulation of small GTPase mediated signal transduction • GO:0072468 signal transduction • axon guidance Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	5909	n/a
Ensembl	ENSG00000076864	n/a
UniProt	P47736	n/a
RefSeq (mRNA)	NM_001145657 NM_001145658 NM_002885 NM_001330383 NM_001350524 NM_001350525 NM_001350526 NM_001350527 NM_001350528	n/a
RefSeq (protein)	NP_001139129 NP_001139130 NP_001317312 NP_002876 NP_001337453 NP_001337454 NP_001337455 NP_001337456 NP_001337457	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn RAP1GAP yw RAP1GAP a elwir hefyd yn RAP1 GTPase activating protein (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 1, band 1p36.12.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn RAP1GAP.

• RAPGAP
• RAP1GA1
• RAP1GAP1
• RAP1GAPII

Llyfryddiaeth

• "Rap1GAP alters leukemia cell differentiation, apoptosis and invasion in vitro. ". Oncol Rep. 2012. PMID 22614916.
• "Rap1GAP regulates renal cell carcinoma invasion. ". Cancer Lett. 2012. PMID 22266190.
• "Rap1GAP inhibits tumor progression in endometrial cancer. ". Biochem Biophys Res Commun. 2017. PMID 28196746.
• "Tumor cell migration and invasion are enhanced by depletion of Rap1 GTPase-activating protein (Rap1GAP). ". J Biol Chem. 2013. PMID 23864657.
• "RAP1GAP inhibits cytoskeletal remodeling and motility in thyroid cancer cells.". Endocr Relat Cancer. 2012. PMID 22696507.