RANBP2

RANBP2
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1RRP, 1XKE, 1Z5S, 3UIN, 3UIO, 3UIP, 4I9Y, 4L6E, 4LQW, 5CLL, 5CLQ, 2LAS
Dynodwyr
Cyfenwau	RANBP2, ADANE, ANE1, IIAE3, NUP358, TRP1, TRP2, RAN binding protein 2
Dynodwyr allanol	OMIM: 601181 HomoloGene: 136803 GeneCards: RANBP2
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • peptidyl-prolyl cis-trans isomerase activity • metal ion binding • ligase activity • GO:0001948, GO:0016582 protein binding • RNA binding • SUMO transferase activity • GO:0005097, GO:0005099, GO:0005100 GTPase activator activity • GO:0032403 protein-containing complex binding • cyclosporin A binding • transferase activity Cydrannau o'r gell • cytosol • nuclear membrane • bilen • nuclear pore • nuclear inclusion body • nuclear pore nuclear basket • cnewyllyn cell • nuclear envelope • lamellae anulatae • intracellular membrane-bounded organelle • cytoplasm • centrosome • mitocondria • nuclear pore cytoplasmic filaments • cytoplasmic periphery of the nuclear pore complex • host cell Prosesau biolegol • mRNA transport • viral transcription • intracellular transport • protein sumoylation • protein peptidyl-prolyl isomerization • mitotic nuclear membrane disassembly • protein folding • regulation of cellular response to heat • protein transport • GO:0022415 viral process • NLS-bearing protein import into nucleus • GO:0046795 intracellular transport of virus • mRNA export from nucleus • tRNA export from nucleus • sister chromatid cohesion • centrosome localization • G1 phase • RNA export from nucleus • ubiquitin-dependent protein catabolic process • GO:0043146 spindle organization • GO:0032320, GO:0032321, GO:0032855, GO:0043089, GO:0032854 positive regulation of GTPase activity • positive regulation of mitotic centrosome separation • response to amphetamine • positive regulation of glucokinase activity • GO:1905616 regulation of gene silencing by miRNA • regulation of glycolytic process • GO:0015915 transport • regulation of gluconeogenesis Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	5903	n/a
Ensembl	ENSG00000153201	n/a
UniProt	P49792	n/a
RefSeq (mRNA)	NM_006267	n/a
RefSeq (protein)	NP_006258	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn RANBP2 yw RANBP2 a elwir hefyd yn RAN binding protein 2 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 2, band 2q13.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn RANBP2.

• ANE1
• TRP1
• TRP2
• ADANE
• IIAE3
• NUP358

Llyfryddiaeth

• "Sumoylation of the GTPase Ran by the RanBP2 SUMO E3 Ligase Complex. ". J Biol Chem. 2015. PMID 26251516.
• "RANBP2 mutation and acute necrotizing encephalopathy: 2 cases and a literature review of the expanding clinico-radiological phenotype. ". Eur J Paediatr Neurol. 2015. PMID 25522933.
• "Selective recruitment of nucleoporins on vaccinia virus factories and the role of Nup358 in viral infection. ". Virology. 2017. PMID 28963881.
• "Nup358 binds to AGO proteins through its SUMO-interacting motifs and promotes the association of target mRNA with miRISC. ". EMBO Rep. 2017. PMID 28039207.
• "Familial acute necrotizing encephalopathy without RANBP2 mutation: Poor outcome.". Pediatr Int. 2016. PMID 27882739.