RALB

RALB
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2KE5, 2KWI
Dynodwyr
Cyfenwau	RALB, RAS like proto-oncogene B
Dynodwyr allanol	OMIM: 179551 HomoloGene: 20632 GeneCards: RALB
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • nucleotide binding • GDP binding • ATPase binding • GTP binding • GO:0001948, GO:0016582 protein binding • GO:0006184 GTPase activity • ubiquitin protein ligase binding Cydrannau o'r gell • bilen • Cellbilen • autophagosome • exocyst • extracellular exosome • intracellular anatomical structure • midbody Prosesau biolegol • positive regulation of protein phosphorylation • positive regulation of autophagosome assembly • cellular response to starvation • negative regulation of protein binding • positive regulation of protein serine/threonine kinase activity • Cellraniad • regulation of exocyst assembly • cellular response to exogenous dsRNA • cell cycle • positive regulation of protein binding • GO:0072468 signal transduction • regulation of exocyst localization • GO:0097285 apoptotic process • Ras protein signal transduction Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	5899	n/a
Ensembl	ENSG00000144118	n/a
UniProt	P11234	n/a
RefSeq (mRNA)	NM_002881 NM_001369400	n/a
RefSeq (protein)	NP_002872 NP_001356329	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn RALB yw RALB a elwir hefyd yn RAS like proto-oncogene B (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 2, band 2q14.2.

Llyfryddiaeth

• "1H, 13C and 15N resonance assignments for the small G protein RalB in its active conformation. ". Biomol NMR Assign. 2007. PMID 19636851.
• "Generation of antibodies specific for the RalA and RalB GTP-binding proteins and determination of their concentration and distribution in human platelets. ". Biochim Biophys Acta. 1996. PMID 8972729.
• "Inhibition of Ral GTPases Using a Stapled Peptide Approach. ". J Biol Chem. 2016. PMID 27334922.
• "Involvement of RalB in the effect of geranylgeranyltransferase I on glioma cell migration and invasion. ". Clin Transl Oncol. 2015. PMID 25573158.
• "Phosphorylation of RalB is important for bladder cancer cell growth and metastasis.". Cancer Res. 2010. PMID 20940393.