RALA

RALA
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1UAD, 1ZC3, 1ZC4, 2A78, 2A9K, 2BOV
Dynodwyr
Cyfenwau	RALA, RAL, RALA Ras like proto-oncogene A, RAS like proto-oncogene A, HINCONS
Dynodwyr allanol	OMIM: 179550 HomoloGene: 3942 GeneCards: RALA
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • Edg-2 lysophosphatidic acid receptor binding • nucleotide binding • GDP binding • myosin binding • ATPase binding • GTP binding • GO:0001948, GO:0016582 protein binding • GO:0006184 GTPase activity • ubiquitin protein ligase binding Cydrannau o'r gell • bilen • focal adhesion • myelin sheath • Cellbilen • endocytic vesicle • cleavage furrow • extracellular exosome • cytoplasmic vesicle membrane • cell surface • Flemming body • intracellular anatomical structure Prosesau biolegol • actin cytoskeleton reorganization • Cellraniad • regulation of exocytosis • chemotaxis • neural tube closure • membrane raft localization • cell cycle • membrane organization • GO:0022415 viral process • positive regulation of filopodium assembly • GO:0072468 signal transduction • exocytosis • Ras protein signal transduction • interleukin-12-mediated signaling pathway Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	5898	n/a
Ensembl	ENSG00000006451	n/a
UniProt	P11233	n/a
RefSeq (mRNA)	NM_005402	n/a
RefSeq (protein)	NP_005393	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn RALA yw RALA a elwir hefyd yn Ras-related protein Ral-A a RAS like proto-oncogene a (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 7, band 7p14.1.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn RALA.

• RAL

Llyfryddiaeth

• "Response to MLN8237 in pancreatic cancer is not dependent on RalA phosphorylation. ". Mol Cancer Ther. 2014. PMID 24222664.
• "miR-181a post-transcriptionally downregulates oncogenic RalA and contributes to growth inhibition and apoptosis in chronic myelogenous leukemia (CML). ". PLoS One. 2012. PMID 22442671.
• "RalA is overactivated in medulloblastoma. ". J Neurooncol. 2016. PMID 27566179.
• "Evaluation and characterization of anti-RalA autoantibody as a potential serum biomarker in human prostate cancer. ". Oncotarget. 2016. PMID 27286458.
• "Agonist-induced changes in RalA activities allows the prediction of the endocytosis of G protein-coupled receptors.". Biochim Biophys Acta. 2016. PMID 26477566.