RAD23B

RAD23B
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1P1A, 1PVE, 1UEL
Dynodwyr
Cyfenwau	RAD23B, HHR23B, HR23B, P58, RAD23 homolog B, nucleotide excision repair protein
Dynodwyr allanol	OMIM: 600062 HomoloGene: 37704 GeneCards: RAD23B
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • single-stranded DNA binding • damaged DNA binding • polyubiquitin modification-dependent protein binding • GO:0001948, GO:0016582 protein binding • ubiquitin binding • proteasome binding Cydrannau o'r gell • XPC complex • proteasome complex • cnewyllyn cell • nucleoplasm • cytoplasm • cytosol Prosesau biolegol • cellular response to DNA damage stimulus • nucleotide-excision repair • global genome nucleotide-excision repair • nucleotide-excision repair, DNA damage recognition • spermatogenesis • embryonic organ development • proteasome-mediated ubiquitin-dependent protein catabolic process • regulation of proteasomal ubiquitin-dependent protein catabolic process • GO:0100026 DNA repair • nucleotide-excision repair, preincision complex assembly • protein folding • protein deubiquitination • cellular response to interleukin-7 • nucleotide-excision repair, DNA duplex unwinding Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	5887	n/a
Ensembl	ENSG00000119318	n/a
UniProt	P54727 Q5W0S4	n/a
RefSeq (mRNA)	NM_002874 NM_001244713 NM_001244724	n/a
RefSeq (protein)	NP_001231642 NP_001231653 NP_002865	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn RAD23B yw RAD23B a elwir hefyd yn UV excision repair protein RAD23 homolog B a RAD23 homolog B, nucleotide excision repair protein (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 9, band 9q31.2.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn RAD23B.

• P58
• HR23B
• HHR23B

Llyfryddiaeth

• "Studies on the intracellular localization of hHR23B. ". Biochem Biophys Res Commun. 2005. PMID 16253613.
• "Solution structure and backbone dynamics of the XPC-binding domain of the human DNA repair protein hHR23B. ". FEBS J. 2005. PMID 15885096.
• "Identification and functional validation of RAD23B as a potential protein in human breast cancer progression. ". J Proteome Res. 2014. PMID 24897598.
• "The association between RAD23B Ala249Val polymorphism and cancer susceptibility: evidence from a meta-analysis. ". PLoS One. 2014. PMID 24643114.
• "Epigenetic therapy using belinostat for patients with unresectable hepatocellular carcinoma: a multicenter phase I/II study with biomarker and pharmacokinetic analysis of tumors from patients in the Mayo Phase II Consortium and the Cancer Therapeutics Research Group.". J Clin Oncol. 2012. PMID 22915658.