RABEP1

RABEP1
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1P4U, 1TU3, 1X79, 4N3Y, 4N3Z, 4Q9U
Dynodwyr
Cyfenwau	RABEP1, RAB5EP, RABPT5, rabaptin, RAB GTPase binding effector protein 1
Dynodwyr allanol	OMIM: 603616 HomoloGene: 3451 GeneCards: RABEP1
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • growth factor activity • protein homodimerization activity • GO:0001948, GO:0016582 protein binding • GO:0005097, GO:0005099, GO:0005100 GTPase activator activity • protein domain specific binding Cydrannau o'r gell • intracellular membrane-bounded organelle • GO:0016023 cytoplasmic vesicle • endocytic vesicle • cytoplasm • recycling endosome • endosome • early endosome • early endosome membrane • GO:0009327 protein-containing complex Prosesau biolegol • membrane fusion • GO:0097285 apoptotic process • protein transport • GO:0032320, GO:0032321, GO:0032855, GO:0043089, GO:0032854 positive regulation of GTPase activity • vesicle-mediated transport • endocytosis • regulation of signaling receptor activity • Golgi to plasma membrane transport • protein localization to ciliary membrane • GO:0072468 signal transduction Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	9135	n/a
Ensembl	ENSG00000029725	n/a
UniProt	Q15276	n/a
RefSeq (mRNA)	NM_001083585 NM_001291581 NM_001291582 NM_004703	n/a
RefSeq (protein)	NP_001077054 NP_001278510 NP_001278511 NP_004694	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn RABEP1 yw RABEP1 a elwir hefyd yn Rabaptin, RAB GTPase binding effector protein 1 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 17, band 17p13.2.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn RABEP1.

• RAB5EP
• RABPT5

Llyfryddiaeth

• "Molecular mechanism for Rabex-5 GEF activation by Rabaptin-5. ". Elife. 2014. PMID 24957337.
• "Global identification of miR-373-regulated genes in breast cancer by quantitative proteomics. ". Proteomics. 2011. PMID 21271679.
• "Perturbation of vacuolar maturation promotes listeriolysin O-independent vacuolar escape during Listeria monocytogenes infection of human cells. ". Cell Microbiol. 2009. PMID 19500109.
• "Association of variants in SH2B1 and RABEP1 with worsening of low-density lipoprotein and glucose parameters in patients treated with psychotropic drugs. ". Gene. 2017. PMID 28694205.
• "ITSN2L Interacts with and Negatively Regulates RABEP1.". Int J Mol Sci. 2015. PMID 26633357.