RAB8A

RAB8A
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 3QBT, 3TNF, 4LHV, 4LHW, 4LHX, 4LHY, 4LHZ, 4LI0
Dynodwyr
Cyfenwau	RAB8A, MEL, RAB8, member RAS oncogene family
Dynodwyr allanol	OMIM: 165040 HomoloGene: 100934 GeneCards: RAB8A
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • nucleotide binding • GDP binding • GTP binding • myosin V binding • GO:0001948, GO:0016582 protein binding • protein kinase binding • GO:0006184 GTPase activity Cydrannau o'r gell • cytoplasm • ciliary basal body • recycling endosome • cytosol • endosome • centrosome • phagocytic vesicle membrane • Golgi apparatus • cell projection • bilen • GO:0097483, GO:0097481 postsynaptic density • synaptic vesicle • Golgi membrane • cilium • ciliary base • neuronal cell body • dendrite • phagocytic vesicle • centriole • extracellular exosome • Cytosgerbwd • GO:0016023 cytoplasmic vesicle • GO:0005578 extracellular matrix • Cellbilen • trans-Golgi network transport vesicle • trans-Golgi network membrane • dendritic spine • recycling endosome membrane • non-motile cilium • secretory granule membrane • midbody • synapse • glutamatergic synapse Prosesau biolegol • regulation of long-term neuronal synaptic plasticity • regulation of protein transport • axonogenesis • vesicle docking involved in exocytosis • protein secretion • regulation of protein localization • cell projection organization • G2/M transition of mitotic cell cycle • Golgi vesicle fusion to target membrane • protein transport • protein localization to plasma membrane • cellular response to insulin stimulus • cilium assembly • ciliary basal body-plasma membrane docking • neurotransmitter receptor transport to postsynaptic membrane • regulation of autophagy • autophagy • post-translational protein modification • regulation of exocytosis • GO:0015915 transport • intracellular protein transport • Rab protein signal transduction • neurotransmitter receptor transport, endosome to postsynaptic membrane • vesicle-mediated transport in synapse Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	4218	n/a
Ensembl	ENSG00000167461	n/a
UniProt	P61006	n/a
RefSeq (mRNA)	NM_005370	n/a
RefSeq (protein)	NP_005361 NP_005361.2	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn RAB8A yw RAB8A a elwir hefyd yn RAB8A, member RAS oncogene family, isoform CRA_a a RAB8A, member RAS oncogene family (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 19, band 19p13.11.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn RAB8A.

• MEL
• RAB8

Llyfryddiaeth

• "Endocytic turnover of Rab8 controls cell polarization. ". J Cell Sci. 2017. PMID 28137756.
• "Protease-Resistant and Cell-Permeable Double-Stapled Peptides Targeting the Rab8a GTPase. ". ACS Chem Biol. 2016. PMID 27336832.
• "Intercellular transfer of transferrin receptor by a contact-, Rab8-dependent mechanism involving tunneling nanotubes. ". FASEB J. 2015. PMID 26220176.
• "RAB8A a new biomarker for endometrial cancer?". World J Surg Oncol. 2014. PMID 25477298.
• "Rab8, a vesicular traffic regulator, is involved in dengue virus infection in HepG2 cells.". Intervirology. 2008. PMID 18724065.