RAB6A

RAB6A
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1YZQ, 2GIL, 3BBP, 3CWZ, 4DKX
Dynodwyr
Cyfenwau	RAB6A, RAB6, member RAS oncogene family
Dynodwyr allanol	OMIM: 179513 HomoloGene: 55697 GeneCards: RAB6A
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • nucleotide binding • protein domain specific binding • GTP binding • myosin V binding • GO:0001948, GO:0016582 protein binding • GO:0006184 GTPase activity Cydrannau o'r gell • Golgi apparatus • bilen • endosome to plasma membrane transport vesicle • trans-Golgi network • extracellular exosome • GO:0016023 cytoplasmic vesicle • trans-Golgi network membrane • cytosol • endoplasmic reticulum membrane • Golgi membrane • Cellbilen • secretory granule membrane Prosesau biolegol • antigen processing and presentation • early endosome to Golgi transport • peptidyl-cysteine methylation • protein localization to Golgi apparatus • protein transport • minus-end-directed organelle transport along microtubule • GO:0022415 viral process • vesicle-mediated transport • retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum • neutrophil degranulation • GO:0015915 transport • intracellular protein transport • intra-Golgi vesicle-mediated transport • Rab protein signal transduction • retrograde transport, endosome to Golgi Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	5870	n/a
Ensembl	ENSG00000175582	n/a
UniProt	P20340	n/a
RefSeq (mRNA)	NM_198896 NM_001243718 NM_001243719 NM_002869	n/a
RefSeq (protein)	NP_001230647 NP_001230648 NP_002860 NP_942599	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn RAB6A yw RAB6A a elwir hefyd yn RAB6A, member RAS oncogene family (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 11, band 11q13.4.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn RAB6A.

• RAB6

Llyfryddiaeth

• "Rab and actomyosin-dependent fission of transport vesicles at the Golgi complex. ". Nat Cell Biol. 2010. PMID 20562865.
• "Rab6 regulates transport and targeting of exocytotic carriers. ". Dev Cell. 2007. PMID 17681140.
• "Targeting of the small GTPase Rab6A' by the Legionella pneumophila effector LidA. ". Infect Immun. 2013. PMID 23569112.
• "Crystal structure of Rab6A'(Q72L) mutant reveals unexpected GDP/Mg²⁺ binding with opened GTP-binding domain. ". Biochem Biophys Res Commun. 2012. PMID 22750005.
• "Rab6 is a modulator of the unfolded protein response: implications for Alzheimer's disease.". J Alzheimers Dis. 2012. PMID 22124028.