RAB3A

RAB3A
Dynodwyr
Cyfenwau	RAB3A, member RAS oncogene family
Dynodwyr allanol	OMIM: 179490 HomoloGene: 20629 GeneCards: RAB3A
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • nucleotide binding • ATPase binding • GTP binding • myosin V binding • protein C-terminus binding • GO:0001948, GO:0016582 protein binding • ATPase activator activity • GTP-dependent protein binding • GO:0006184 GTPase activity • GDP-dissociation inhibitor binding Cydrannau o'r gell • extracellular vesicle • endosome • clathrin-sculpted monoamine transport vesicle membrane • bilen • synaptic vesicle • Cellbilen • clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane • clathrin-sculpted acetylcholine transport vesicle membrane • axon • terminal bouton • acrosomal vesicle • intracellular organelle • clathrin-sculpted glutamate transport vesicle membrane • cytosol • secretory granule membrane • anchored component of synaptic vesicle membrane • fesigl • GO:0009327 protein-containing complex • presynaptic active zone • secretory granule • perinuclear region of cytoplasm Prosesau biolegol • respiratory system process • positive regulation of ATP-dependent activity • axonogenesis • lung development • synaptic vesicle exocytosis • regulation of short-term neuronal synaptic plasticity • evoked neurotransmitter secretion • mitochondrion organization • response to electrical stimulus • post-embryonic development • constitutive secretory pathway • maintenance of presynaptic active zone structure • glutamate secretion • regulation of exocytosis • regulation of synaptic vesicle fusion to presynaptic active zone membrane • neuromuscular synaptic transmission • synaptic vesicle recycling • sensory perception of touch • protein transport • positive regulation of exocytosis • synaptic vesicle maturation • GO:0010554 neurotransmitter secretion • positive regulation of regulated secretory pathway • exocytosis • neutrophil degranulation • post-translational protein modification • GO:0015915 transport • intracellular protein transport • vesicle docking involved in exocytosis • protein secretion • Rab protein signal transduction • protein localization to plasma membrane • plasma membrane repair • regulation of synaptic vesicle priming • synaptic vesicle transport • acrosomal vesicle exocytosis • regulation of synaptic vesicle exocytosis • calcium-ion regulated exocytosis • synaptic vesicle clustering Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	5864	n/a
Ensembl	ENSG00000105649	n/a
UniProt	P20336	n/a
RefSeq (mRNA)	NM_002866	n/a
RefSeq (protein)	NP_002857 NP_002857.1	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn RAB3A yw RAB3A a elwir hefyd yn H.sapiens ras-related Hrab3A protein a RAB3A, member RAS oncogene family (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 19, band 19p13.11.

Llyfryddiaeth

• "Cholesterol content regulates acrosomal exocytosis by enhancing Rab3A plasma membrane association. ". Dev Biol. 2005. PMID 16099449.
• "DNA variants in the human RAB3A gene are not associated with autism. ". Genes Brain Behav. 2004. PMID 15005721.
• "3D structure generation, virtual screening and docking of human Ras-associated binding (Rab3A) protein involved in tumourigenesis. ". Mol Biol Rep. 2014. PMID 24652202.
• "Membrane-permeant Rab3A triggers acrosomal exocytosis in living human sperm. ". FASEB J. 2007. PMID 17625073.
• "Variants in the RAB3A gene are not associated with mental retardation in the Chinese population.". Neurosci Lett. 2006. PMID 16584842.