RAB2A

RAB2A
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1Z0A
Dynodwyr
Cyfenwau	RAB2A, LHX, RAB2, member RAS oncogene family
Dynodwyr allanol	OMIM: 179509 HomoloGene: 20628 GeneCards: RAB2A
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • nucleotide binding • GDP binding • GTP binding • GO:0001948, GO:0016582 protein binding • GO:0006184 GTPase activity Cydrannau o'r gell • endoplasmic reticulum membrane • bilen • melanosome • Golgi membrane • lysosomal membrane • Reticwlwm endoplasmig • endoplasmic reticulum-Golgi intermediate compartment membrane • extracellular exosome • cnewyllyn cell • cytosol • Golgi apparatus • intracellular anatomical structure Prosesau biolegol • Golgi organization • endoplasmic reticulum to Golgi vesicle-mediated transport • protein transport • vesicle-mediated transport • post-translational protein modification • GO:0015915 transport • intracellular protein transport • Rab protein signal transduction • small GTPase mediated signal transduction Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	5862	n/a
Ensembl	ENSG00000104388	n/a
UniProt	P61019	n/a
RefSeq (mRNA)	NM_002865 NM_001242644	n/a
RefSeq (protein)	NP_001229573 NP_002856	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn RAB2A yw RAB2A a elwir hefyd yn Ras-related protein Rab-2A (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 8, band 8q12.1-q12.2.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn RAB2A.

• LHX
• RAB2

Llyfryddiaeth

• "Identification of a Brucella spp. secreted effector specifically interacting with human small GTPase Rab2. ". Cell Microbiol. 2011. PMID 21501366.
• "Rab2 is essential for the maturation of pre-Golgi intermediates. ". J Biol Chem. 1996. PMID 8910601.
• "RAB2A controls MT1-MMP endocytic and E-cadherin polarized Golgi trafficking to promote invasive breast cancer programs. ". EMBO Rep. 2016. PMID 27255086.
• "RAB2A Polymorphism impacts prefrontal morphology, functional connectivity, and working memory. ". Hum Brain Mapp. 2015. PMID 26249043.
• "Molecular structure of the Brucella abortus metalloprotein RicA, a Rab2-binding virulence effector.". Biochemistry. 2013. PMID 24251537.