RAB25

RAB25
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2OIL, 3TSO
Dynodwyr
Cyfenwau	RAB25, CATX-8, RAB11C, member RAS oncogene family
Dynodwyr allanol	OMIM: 612942 HomoloGene: 22995 GeneCards: RAB25
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • nucleotide binding • GTP binding • myosin V binding • GO:0001948, GO:0016582 protein binding • GO:0006184 GTPase activity Cydrannau o'r gell • pseudopodium membrane • Cellbilen • cell projection • pseudopodium • extracellular exosome • GO:0016023 cytoplasmic vesicle • bilen • endosome • recycling endosome Prosesau biolegol • protein transport • regulation of vesicle-mediated transport • positive regulation of epithelial cell migration • epithelial cell morphogenesis • positive regulation of cell population proliferation • pseudopodium organization • GO:0015915 transport • intracellular protein transport • exocytosis • Rab protein signal transduction Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	57111	n/a
Ensembl	ENSG00000132698	n/a
UniProt	P57735	n/a
RefSeq (mRNA)	NM_020387	n/a
RefSeq (protein)	NP_065120	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn RAB25 yw RAB25 a elwir hefyd yn RAB25, member RAS oncogene family (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 1, band 1q22.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn RAB25.

• CATX-8
• RAB11C

Llyfryddiaeth

• "Expression of Ras-related protein 25 predicts chemotherapy resistance and prognosis in advanced non-small cell lung cancer. ". Genet Mol Res. 2015. PMID 26535714.
• "Rab25 upregulation correlates with the proliferation, migration, and invasion of renal cell carcinoma. ". Biochem Biophys Res Commun. 2015. PMID 25686498.
• "Knockdown of Ras-Related Protein 25 (Rab25) Inhibits the In Vitro Cytotoxicity and In Vivo Antitumor Activity of Human Glioblastoma Multiforme Cells. ". Oncol Res. 2017. PMID 28281975.
• "RAB25 expression is epigenetically downregulated in oral and oropharyngeal squamous cell carcinoma with lymph node metastasis. ". Epigenetics. 2016. PMID 27379752.
• "Overexpression of Rab25 promotes hepatocellular carcinoma cell proliferation and invasion.". Tumour Biol. 2016. PMID 26692100.