RAB21

RAB21
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1YZT, 1YZU, 1Z08, 1Z0I, 2OT3
Dynodwyr
Cyfenwau	RAB21, member RAS oncogene family
Dynodwyr allanol	OMIM: 612398 HomoloGene: 8991 GeneCards: RAB21
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • nucleotide binding • GDP binding • GTP binding • GO:0001948, GO:0016582 protein binding • GO:0006184 GTPase activity Cydrannau o'r gell • endosome • Golgi apparatus • endoplasmic reticulum membrane • bilen • focal adhesion • vesicle membrane • Golgi membrane • Golgi cisterna membrane • trans-Golgi network • Reticwlwm endoplasmig • neuron projection • cytoplasmic side of plasma membrane • cytoplasmic side of early endosome membrane • cleavage furrow • extracellular exosome • cytoplasmic vesicle membrane • GO:0016023 cytoplasmic vesicle • axon cytoplasm • cytosol • early endosome membrane • early endosome • synapse Prosesau biolegol • positive regulation of receptor-mediated endocytosis • regulation of axon extension • anterograde axonal transport • regulation of exocytosis • positive regulation of dendrite morphogenesis • protein transport • positive regulation of early endosome to late endosome transport • GO:0015915 transport • intracellular protein transport • Rab protein signal transduction • GO:0072468 signal transduction Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	23011	n/a
Ensembl	ENSG00000080371	n/a
UniProt	Q9UL25	n/a
RefSeq (mRNA)	NM_014999	n/a
RefSeq (protein)	NP_055814	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn RAB21 yw RAB21 a elwir hefyd yn RAB21, member RAS oncogene family (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 12, band 12q21.1.

Llyfryddiaeth

• "Integrin trafficking regulated by Rab21 is necessary for cytokinesis. ". Dev Cell. 2008. PMID 18804435.
• "[Multiadaptor 4.1 and RanBP9 protein family members as putative interaction partners for VARP, a Rab21 GTPase guanine nucleotide exchange factor]. ". Mol Biol (Mosk). 2007. PMID 18318119.
• "Cytokinesis failure due to derailed integrin traffic induces aneuploidy and oncogenic transformation in vitro and in vivo. ". Oncogene. 2012. PMID 22120710.
• "A chemical biology screen reveals a role for Rab21-mediated control of actomyosin contractility in fibroblast-driven cancer invasion. ". Br J Cancer. 2010. PMID 19953096.
• "Rabs and cancer cell motility.". Cell Motil Cytoskeleton. 2009. PMID 19418559.