QDPR

QDPR
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1HDR
Dynodwyr
Cyfenwau	QDPR, DHPR, PKU2, SDR33C1, quinoid dihydropteridine reductase, HDHPR
Dynodwyr allanol	OMIM: 612676 HomoloGene: 271 GeneCards: QDPR
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • protein homodimerization activity • 6,7-dihydropteridine reductase activity • NADPH binding • NADH binding • electron transfer activity • oxidoreductase activity Cydrannau o'r gell • cytoplasm • cytosol • mitocondria • neuron projection • extracellular exosome Prosesau biolegol • response to glucagon • cellular amino acid metabolic process • L-phenylalanine catabolic process • dihydrobiopterin metabolic process • response to lead ion • response to aluminum ion • tetrahydrobiopterin biosynthetic process • liver development • electron transport chain Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	5860	n/a
Ensembl	ENSG00000151552	n/a
UniProt	P09417	n/a
RefSeq (mRNA)	NM_000320 NM_001306140	n/a
RefSeq (protein)	NP_000311 NP_001293069	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn QDPR yw QDPR a elwir hefyd yn Dihydropteridine reductase a Quinoid dihydropteridine reductase (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 4, band 4p15.32.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn QDPR.

• DHPR
• PKU2
• SDR33C1

Llyfryddiaeth

• "QDPR gene mutation and clinical follow-up in Chinese patients with dihydropteridine reductase deficiency. ". World J Pediatr. 2014. PMID 25124972.
• "Perturbed 6-tetrahydrobiopterin recycling via decreased dihydropteridine reductase in vitiligo: more evidence for H2O2 stress. ". J Invest Dermatol. 2004. PMID 15009710.
• "Molecular analysis of 16 Turkish families with DHPR deficiency using denaturing gradient gel electrophoresis (DGGE). ". Hum Genet. 2000. PMID 11153907.
• "A series of mutations in the dihydropteridine reductase gene resulting in either abnormal RNA splicing or DHPR protein defects. Mutations in brief no. 244. Online. ". Hum Mutat. 1999. PMID 10408783.
• "Dihydropteridine reductase deficiency: physical structure of the QDPR gene, identification of two new mutations and genotype-phenotype correlations.". Hum Mutat. 1998. PMID 9744478.