PUM2

PUM2
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 3Q0Q, 3Q0R, 3Q0S
Dynodwyr
Cyfenwau	PUM2, PUMH2, PUML2, pumilio RNA binding family member 2
Dynodwyr allanol	OMIM: 607205 HomoloGene: 69183 GeneCards: PUM2
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • GO:0001948, GO:0016582 protein binding • RNA binding • mRNA 3'-UTR binding • miRNA binding Cydrannau o'r gell • perinuclear region of cytoplasm • cytoplasmic stress granule • nuclear membrane • cytoplasm • cytosol Prosesau biolegol • regulation of chromosome segregation • GO:1905616 regulation of gene silencing by miRNA • positive regulation of RIG-I signaling pathway • regulation of translation • regulation of mRNA stability • GO:1905618 positive regulation of gene silencing by miRNA • stress granule assembly • posttranscriptional regulation of gene expression • production of miRNAs involved in gene silencing by miRNA Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	23369	n/a
Ensembl	ENSG00000055917	n/a
UniProt	Q8TB72	n/a
RefSeq (mRNA)	NM_001282752 NM_001282790 NM_001282791 NM_015317 NM_001352917 NM_001352918 NM_001352919 NM_001352920 NM_001352923 NM_001352925 NM_001352926 NM_001352927 NM_001352928 NM_001352929 NM_001352930	n/a
RefSeq (protein)	NP_001269681 NP_001269719 NP_001269720 NP_056132 NP_001339846 NP_001339847 NP_001339848 NP_001339849 NP_001339852 NP_001339854 NP_001339855 NP_001339856 NP_001339857 NP_001339858 NP_001339859	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn PUM2 yw PUM2 a elwir hefyd yn Pumilio RNA binding family member 2 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 2, band 2p24.1.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn PUM2.

• PUMH2
• PUML2

Llyfryddiaeth

• "Candidate mRNAs interacting with fertility protein PUMILIO2 in the human germ line. ". Reprod Biol. 2006. PMID 16967088.
• "Bespoke RNA recognition by Pumilios. ". Biochem Soc Trans. 2015. PMID 26517885.
• "Pseudouridine and N6-methyladenosine modifications weaken PUF protein/RNA interactions. ". RNA. 2017. PMID 28138061.
• "PUMILIO-2 is involved in the positive regulation of cellular proliferation in human adipose-derived stem cells. ". Stem Cells Dev. 2012. PMID 21649561.
• "Polymorphisms of the human PUMILIO2 gene and male sterility.". Mol Reprod Dev. 2007. PMID 17154300.