PTPRR

PTPRR
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2A8B
Dynodwyr
Cyfenwau	PTPRR, EC-PTP, PCPTP1, PTP-SL, PTPBR7, PTPRQ, protein tyrosine phosphatase, receptor type R, protein tyrosine phosphatase receptor type R
Dynodwyr allanol	OMIM: 602853 HomoloGene: 2135 GeneCards: PTPRR
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • phosphoprotein phosphatase activity • GO:0098519, GO:0098518 phosphatase activity • GO:0001948, GO:0016582 protein binding • protein tyrosine phosphatase activity • transmembrane receptor protein tyrosine phosphatase activity • protein kinase binding • hydrolase activity Cydrannau o'r gell • integral component of membrane • bilen • Cellbilen • cell junction • perinuclear region of cytoplasm • extracellular space • cytoplasm • cytosol Prosesau biolegol • GO:0016576 protein dephosphorylation • in utero embryonic development • ERBB2 signaling pathway • regulation of homophilic cell adhesion • negative regulation of ERK1 and ERK2 cascade • peptidyl-tyrosine dephosphorylation • negative regulation of epithelial cell migration • GO:0098501, GO:0098502, GO:0006286 dephosphorylation Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	5801	n/a
Ensembl	ENSG00000153233	n/a
UniProt	Q15256	n/a
RefSeq (mRNA)	NM_001207015 NM_001207016 NM_002849 NM_130846	n/a
RefSeq (protein)	NP_001193944 NP_001193945 NP_002840 NP_570897	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn PTPRR yw PTPRR a elwir hefyd yn Protein tyrosine phosphatase, receptor type R (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 12, band 12q15.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn PTPRR.

• PTPRQ
• EC-PTP
• PCPTP1
• PTP-SL
• PTPBR7

Llyfryddiaeth

• "The protein tyrosine phosphatase receptor type R gene is an early and frequent target of silencing in human colorectal tumorigenesis. ". Mol Cancer. 2009. PMID 20015382.
• "Immunohistochemical and Western blot analysis of two protein tyrosine phosphatase receptors, R and Z1, in colorectal carcinoma, colon adenoma and normal colon tissues. ". Histol Histopathol. 2014. PMID 24242166.
• "Polymorphism of ERK/PTPRR Genes in Major Depressive Disorder at Resting-State Brain Function. ". Dev Neuropsychol. 2017. PMID 28467119.
• "Androgen-regulation of the protein tyrosine phosphatase PTPRR activates ERK1/2 signalling in prostate cancer cells. ". BMC Cancer. 2015. PMID 25592066.
• "Gender-specific role of the protein tyrosine phosphatase receptor type R gene in major depressive disorder.". J Affect Disord. 2012. PMID 22100128.