PTPN9

PTPN9
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2PA5, 4GE2, 4GE5, 4GE6, 4ICZ
Dynodwyr
Cyfenwau	PTPN9, MEG2, PTPMEG2, protein tyrosine phosphatase, non-receptor type 9, protein tyrosine phosphatase non-receptor type 9
Dynodwyr allanol	OMIM: 600768 HomoloGene: 2121 GeneCards: PTPN9
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • protein tyrosine phosphatase activity • phosphoprotein phosphatase activity • hydrolase activity • non-membrane spanning protein tyrosine phosphatase activity • GO:0098519, GO:0098518 phosphatase activity • GO:0001948, GO:0016582 protein binding Cydrannau o'r gell • cytoplasm • nucleoplasm • neuron projection terminus Prosesau biolegol • GO:0016576 protein dephosphorylation • GO:0098501, GO:0098502, GO:0006286 dephosphorylation • cellular response to cytokine stimulus • negative regulation of neuron projection development • peptidyl-tyrosine dephosphorylation • positive regulation of protein localization to plasma membrane Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	5780	n/a
Ensembl	ENSG00000169410	n/a
UniProt	P43378	n/a
RefSeq (mRNA)	NM_002833	n/a
RefSeq (protein)	NP_002824	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn PTPN9 yw PTPN9 a elwir hefyd yn Protein tyrosine phosphatase, non-receptor type 9 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 15, band 15q24.2.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn PTPN9.

• MEG2
• PTPMEG2

Llyfryddiaeth

• "PTP-MEG2 is activated in polycythemia vera erythroid progenitor cells and is required for growth and expansion of erythroid cells. ". Blood. 2003. PMID 12920026.
• "Purification and characterization of protein tyrosine phosphatase PTP-MEG2. ". J Cell Biochem. 2002. PMID 12112018.
• "Downregulated Expression of PTPN9 Contributes to Human Hepatocellular Carcinoma Growth and Progression. ". Pathol Oncol Res. 2016. PMID 26715439.
• "Association of protein-tyrosine phosphatase MEG2 via its Sec14p homology domain with vesicle-trafficking proteins. ". J Biol Chem. 2007. PMID 17387180.
• "Homotypic secretory vesicle fusion induced by the protein tyrosine phosphatase MEG2 depends on polyphosphoinositides in T cells.". J Immunol. 2003. PMID 14662869.