PTPN7

PTPN7
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1ZC0, 2A3K, 2GP0, 2GPH, 2HVL, 2QDC, 2QDM, 2QDP, 3D42, 3D44, 3O4S, 3O4T, 3O4U
Dynodwyr
Cyfenwau	PTPN7, BPTP-4, HEPTP, LC-PTP, LPTP, PTPNI, protein tyrosine phosphatase, non-receptor type 7, protein tyrosine phosphatase non-receptor type 7
Dynodwyr allanol	OMIM: 176889 HomoloGene: 15411 GeneCards: PTPN7
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • protein tyrosine phosphatase activity • GO:0098519, GO:0098518 phosphatase activity • GO:0001948, GO:0016582 protein binding • phosphoprotein phosphatase activity • hydrolase activity Cydrannau o'r gell • cytoplasmic side of plasma membrane • Cytosgerbwd • cytoplasm • cytosol • nucleoplasm Prosesau biolegol • GO:0098501, GO:0098502, GO:0006286 dephosphorylation • peptidyl-tyrosine dephosphorylation • GO:0016576 protein dephosphorylation • cellular response to cytokine stimulus Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	5778	n/a
Ensembl	ENSG00000143851	n/a
UniProt	P35236	n/a
RefSeq (mRNA)	NM_001199797 NM_002832 NM_080588 NM_080589 NM_001364877 NM_001364878	n/a
RefSeq (protein)	NP_001186726 NP_002823 NP_542155 NP_001351806 NP_001351807	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn PTPN7 yw PTPN7 a elwir hefyd yn Tyrosine-protein phosphatase non-receptor type 7 a Protein tyrosine phosphatase, non-receptor type 7 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 1, band 1q32.1.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn PTPN7.

• LPTP
• HEPTP
• PTPNI
• BPTP-4
• LC-PTP

Llyfryddiaeth

• "Negative regulation of T cell antigen receptor signal transduction by hematopoietic tyrosine phosphatase (HePTP). ". J Biol Chem. 1998. PMID 9624114.
• "A hematopoietic protein tyrosine phosphatase (HePTP) gene that is amplified and overexpressed in myeloid malignancies maps to chromosome 1q32.1. ". Leukemia. 1994. PMID 8309248.
• "Structural basis of substrate recognition by hematopoietic tyrosine phosphatase. ". Biochemistry. 2008. PMID 19053285.
• "Structure of the hematopoietic tyrosine phosphatase (HePTP) catalytic domain: structure of a KIM phosphatase with phosphate bound at the active site. ". J Mol Biol. 2005. PMID 16226275.
• "A kinetic approach for the study of protein phosphatase-catalyzed regulation of protein kinase activity.". Biochemistry. 2002. PMID 12056917.