PTPN18

PTPN18
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2OC3, 4GFU, 4GFV, 4NND
Dynodwyr
Cyfenwau	PTPN18, BDP1, PTP-HSCF, protein tyrosine phosphatase, non-receptor type 18, protein tyrosine phosphatase non-receptor type 18
Dynodwyr allanol	OMIM: 606587 HomoloGene: 74971 GeneCards: PTPN18
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • GO:0001948, GO:0016582 protein binding • non-membrane spanning protein tyrosine phosphatase activity • GO:0098519, GO:0098518 phosphatase activity • phosphoprotein phosphatase activity • hydrolase activity • protein tyrosine phosphatase activity Cydrannau o'r gell • cnewyllyn cell • cytoplasm • cytosol • nucleoplasm Prosesau biolegol • GO:0016576 protein dephosphorylation • peptidyl-tyrosine dephosphorylation • GO:0098501, GO:0098502, GO:0006286 dephosphorylation • ERBB2 signaling pathway • negative regulation of ERBB signaling pathway • cellular response to cytokine stimulus • blastocyst formation Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	26469	n/a
Ensembl	ENSG00000072135	n/a
UniProt	Q99952	n/a
RefSeq (mRNA)	NM_001142370 NM_014369	n/a
RefSeq (protein)	NP_001135842 NP_055184	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn PTPN18 yw PTPN18 a elwir hefyd yn Protein tyrosine phosphatase, non-receptor type 18 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 2, band 2q21.1.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn PTPN18.

• BDP1
• PTP-HSCF

Llyfryddiaeth

• "Identification of a novel polyproline recognition site in the cytoskeletal associated protein, proline serine threonine phosphatase interacting protein. ". J Biol Chem. 1998. PMID 9422760.
• "The catalytic region and PEST domain of PTPN18 distinctly regulate the HER2 phosphorylation and ubiquitination barcodes. ". Cell Res. 2014. PMID 25081058.
• "A bioinformatics analysis of protein tyrosine phosphatases in humans. ". DNA Res. 2005. PMID 16303740.
• "Characterization of the PEST family protein tyrosine phosphatase BDP1. ". Oncogene. 1996. PMID 8950995.
• "Protein tyrosine phosphatase PTP20 induces actin cytoskeleton reorganization by dephosphorylating p190 RhoGAP in rat ovarian granulosa cells stimulated with follicle-stimulating hormone.". Mol Endocrinol. 2003. PMID 12554790.