PTPN14

PTPN14
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2BZL
Dynodwyr
Cyfenwau	PTPN14, PEZ, PTP36, protein tyrosine phosphatase, non-receptor type 14, CATLPH, protein tyrosine phosphatase non-receptor type 14, PTPD2
Dynodwyr allanol	OMIM: 603155 HomoloGene: 3941 GeneCards: PTPN14
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • phosphoprotein phosphatase activity • hydrolase activity • GO:0098519, GO:0098518 phosphatase activity • receptor tyrosine kinase binding • GO:0001104 transcription coregulator activity • GO:0001948, GO:0016582 protein binding • protein tyrosine phosphatase activity Cydrannau o'r gell • cnewyllyn cell • cytoplasm • Cytosgerbwd • nucleoplasm Prosesau biolegol • negative regulation of cell population proliferation • GO:0009373 regulation of transcription, DNA-templated • GO:0016576 protein dephosphorylation • regulation of protein export from nucleus • transcription, DNA-templated • GO:0098501, GO:0098502, GO:0006286 dephosphorylation • lymphangiogenesis • peptidyl-tyrosine dephosphorylation • cellular response to cytokine stimulus • regulation of nucleic acid-templated transcription Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	5784	n/a
Ensembl	ENSG00000152104	n/a
UniProt	Q15678	n/a
RefSeq (mRNA)	NM_005401	n/a
RefSeq (protein)	NP_005392	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn PTPN14 yw PTPN14 a elwir hefyd yn Protein tyrosine phosphatase, non-receptor type 14 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 1, band 1q32.3-q41.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn PTPN14.

• PEZ
• PTP36
• CATLPH

Llyfryddiaeth

• "Effects of overexpression of PTP36, a putative protein tyrosine phosphatase, on cell adhesion, cell growth, and cytoskeletons in HeLa cells. ". J Biol Chem. 1999. PMID 10212280.
• "Pez: a novel human cDNA encoding protein tyrosine phosphatase- and ezrin-like domains. ". Biochem Biophys Res Commun. 1995. PMID 7733990.
• "Identification and functional characterization of p130Cas as a substrate of protein tyrosine phosphatase nonreceptor 14. ". Oncogene. 2013. PMID 22710723.
• "Crystal structure of human protein tyrosine phosphatase 14 (PTPN14) at 1.65-A resolution. ". Proteins. 2006. PMID 16534812.
• "Regulation of phosphorylation level and distribution of PTP36, a putative protein tyrosine phosphatase, by cell-substrate adhesion.". J Biol Chem. 1999. PMID 10400706.