PTPN13

PTPN13
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1D5G, 1Q7X, 1WCH, 2M0Z, 2M10, 3LNX, 3LNY, 3PDZ
Dynodwyr
Cyfenwau	PTPN13, FAP-1, PNP1, PTP-BAS, PTP-BL, PTP1E, PTPL1, PTPLE, hPTP1E, protein tyrosine phosphatase, non-receptor type 13, protein tyrosine phosphatase non-receptor type 13
Dynodwyr allanol	OMIM: 600267 HomoloGene: 7909 GeneCards: PTPN13
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • protein tyrosine phosphatase activity • GO:0098519, GO:0098518 phosphatase activity • phosphatidylinositol 3-kinase regulatory subunit binding • GO:0001948, GO:0016582 protein binding • phosphoprotein phosphatase activity • hydrolase activity Cydrannau o'r gell • cytoplasm • cell body • neuron projection • cell projection • extracellular exosome • Cytosgerbwd • cnewyllyn cell • lamellipodium • Cellbilen • nucleoplasm Prosesau biolegol • GO:0016576 protein dephosphorylation • peptidyl-tyrosine dephosphorylation • regulation of phosphatidylinositol 3-kinase signaling • GO:0098501, GO:0098502, GO:0006286 dephosphorylation • phosphatidylinositol biosynthetic process • GO:0033128 negative regulation of protein phosphorylation • cellular response to cytokine stimulus • bicellular tight junction assembly Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	5783	n/a
Ensembl	ENSG00000163629	n/a
UniProt	Q12923	n/a
RefSeq (mRNA)	NM_006264 NM_080683 NM_080684 NM_080685	n/a
RefSeq (protein)	NP_006255 NP_542414 NP_542415 NP_542416	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn PTPN13 yw PTPN13 a elwir hefyd yn Tyrosine-protein phosphatase non-receptor type 13 a Protein tyrosine phosphatase, non-receptor type 13 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 4, band 4q21.3.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn PTPN13.

• PNP1
• FAP-1
• PTP1E
• PTPL1
• PTPLE
• PTP-BL
• hPTP1E
• PTP-BAS

Llyfryddiaeth

• "Effect of viscogens on the kinetic response of a photoperturbed allosteric protein. ". J Chem Phys. 2014. PMID 25494785.
• "Long-range conformational transition of a photoswitchable allosteric protein: molecular dynamics simulation study. ". J Phys Chem B. 2014. PMID 25365469.
• "High-resolution crystal structure of the PDZ1 domain of human protein tyrosine phosphatase PTP-Bas. ". Biochem Biophys Res Commun. 2016. PMID 27544031.
• "Tumour-suppressive role of PTPN13 in hepatocellular carcinoma and its clinical significance. ". Tumour Biol. 2016. PMID 26801674.
• "Allosteric communication pathways and thermal rectification in PDZ-2 protein: a computational study.". J Phys Chem B. 2015. PMID 25933631.