PTPA

PTPA
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2G62, 2HV6, 2HV7, 2IXM, 4LAC, 4NY3
Dynodwyr
Cyfenwau	PTPA, PP2A, PR53, PPP2R4, protein phosphatase 2 regulatory subunit 4, protein phosphatase 2 phosphatase activator
Dynodwyr allanol	OMIM: 600756 HomoloGene: 6149 GeneCards: PTPA
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • nucleotide binding • protein tyrosine phosphatase activator activity • protein homodimerization activity • isomerase activity • peptidyl-prolyl cis-trans isomerase activity • ATPase activity • GO:0001948, GO:0016582 protein binding • protein heterodimerization activity • protein phosphatase 2A binding • phosphatase activator activity • signaling receptor binding • ATP binding • protein phosphatase regulator activity Cydrannau o'r gell • cytoplasm • calcium channel complex • protein phosphatase type 2A complex • nucleoplasm • extracellular exosome • cnewyllyn cell Prosesau biolegol • negative regulation of protein dephosphorylation • positive regulation of protein dephosphorylation • regulation of phosphoprotein phosphatase activity • positive regulation of phosphoprotein phosphatase activity • positive regulation of apoptotic process • negative regulation of phosphoprotein phosphatase activity • protein peptidyl-prolyl isomerization • GO:0043148 mitotic spindle organization Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	5524	n/a
Ensembl	ENSG00000119383	n/a
UniProt	Q15257	n/a
RefSeq (mRNA)	NM_001193397 NM_001271832 NM_021131 NM_178000 NM_178001 NM_178002 NM_178003	n/a
RefSeq (protein)	NP_001180326 NP_001258761 NP_066954 NP_821067 NP_821068 NP_821070	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn PTPA yw PTPA a elwir hefyd yn Protein phosphatase 2 phosphatase activator (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 9, band 9q34.11.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn PTPA.

• PP2A
• PR53
• PPP2R4

Llyfryddiaeth

• "A PP2A-B55 recognition signal controls substrate dephosphorylation kinetics during mitotic exit. ". J Cell Biol. 2016. PMID 27551054.
• "PP2A as a master regulator of the cell cycle. ". Crit Rev Biochem Mol Biol. 2016. PMID 26906453.
• "Effects of fostriecin on β2-adrenoceptor-driven responses in human mast cells. ". J Immunotoxicol. 2017. PMID 28090813.
• "Temporal Analysis of PP2A Phosphatase Activity During Insulin Stimulation Using a Direct Activity Probe. ". ACS Chem Biol. 2016. PMID 27805358.
• "Association of functional genetic variation in PP2A with prefrontal working memory processing.". Behav Brain Res. 2017. PMID 27591184.