PTP4A1

PTP4A1
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1RXD, 1XM2
Dynodwyr
Cyfenwau	PTP4A1, HH72, PRL-1, PRL1, PTP(CAAX1), PTPCAAX1, protein tyrosine phosphatase type IVA, member 1, protein tyrosine phosphatase 4A1
Dynodwyr allanol	OMIM: 601585 HomoloGene: 2587 GeneCards: PTP4A1
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • phosphoprotein phosphatase activity • GO:0098519, GO:0098518 phosphatase activity • protein tyrosine phosphatase activity • hydrolase activity • protein tyrosine/serine/threonine phosphatase activity • GO:0001948, GO:0016582 protein binding Cydrannau o'r gell • cytoplasm • endosome • bilen • Cellbilen • spindle • early endosome • Reticwlwm endoplasmig • cytoplasmic side of plasma membrane • Cytosgerbwd • cnewyllyn cell Prosesau biolegol • positive regulation of cell migration • GO:0016576 protein dephosphorylation • multicellular organism development • cell cycle • GO:0098501, GO:0098502, GO:0006286 dephosphorylation • peptidyl-tyrosine dephosphorylation Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	7803	n/a
Ensembl	ENSG00000112245	n/a
UniProt	Q93096	n/a
RefSeq (mRNA)	NM_003463	n/a
RefSeq (protein)	NP_003454	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn PTP4A1 yw PTP4A1 a elwir hefyd yn Protein tyrosine phosphatase type IVA, member 1 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 6, band 6q12.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn PTP4A1.

• HH72
• PRL1
• PRL-1
• PTPCAAX1
• PTP(CAAX1)

Llyfryddiaeth

• "Impact of oncogenic protein tyrosine phosphatases in cancer. ". Anticancer Agents Med Chem. 2012. PMID 21707506.
• "PRL-3 phosphatase and cancer metastasis. ". J Cell Biochem. 2010. PMID 21053359.
• "Oncogenic function and prognostic significance of protein tyrosine phosphatase PRL-1 in hepatocellular carcinoma. ". Oncotarget. 2014. PMID 25003523.
• "Identification of PRL1 as a novel diagnostic and therapeutic target for castration-resistant prostate cancer by the Escherichia coli ampicillin secretion trap (CAST) method. ". Urol Oncol. 2014. PMID 24968948.
• "Increased expression of PRL-1 protein correlates with shortened patient survival in human hepatocellular carcinoma.". Clin Transl Oncol. 2012. PMID 22484636.