PTGDS

PTGDS
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 4OS8, 2WWP, 3O19, 3O22, 3O2Y, 4IMN, 4IMO, 4ORR, 4ORS, 4ORU, 4ORW, 4ORX, 4ORY, 4OS0, 4OS3
Dynodwyr
Cyfenwau	PTGDS, L-PGDS, LPGDS, PDS, PGD2, PGDS, PGDS2, prostaglandin D2 synthase
Dynodwyr allanol	OMIM: 176803 HomoloGene: 737 GeneCards: PTGDS
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • transporter activity • isomerase activity • fatty acid binding • prostaglandin-D synthase activity • GO:0001948, GO:0016582 protein binding • small molecule binding • retinoid binding Cydrannau o'r gell • cytoplasm • Golgi apparatus • rough endoplasmic reticulum • nuclear membrane • endoplasmic reticulum membrane • bilen • extracellular region • Reticwlwm endoplasmig • perinuclear region of cytoplasm • extracellular exosome • cnewyllyn cell • extracellular space Prosesau biolegol • prostaglandin metabolic process • lipid metabolism • cyclooxygenase pathway • fatty acid metabolic process • fatty acid biosynthetic process • prostaglandin biosynthetic process • regulation of circadian sleep/wake cycle, sleep • GO:0015915 transport Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	5730	n/a
Ensembl	ENSG00000107317	n/a
UniProt	P41222 Q5SQ11	n/a
RefSeq (mRNA)	NM_000954	n/a
RefSeq (protein)	NP_000945	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn PTGDS yw PTGDS a elwir hefyd yn Prostaglandin-H2 D-isomerase a Prostaglandin D2 synthase (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 9, band 9q34.3.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn PTGDS.

• PDS
• PGD2
• PGDS
• LPGDS
• PGDS2
• L-PGDS

Llyfryddiaeth

• "Sample-dependent diagnostic accuracy of prostaglandin D synthase in cerebrospinal fluid leak. ". Clin Biochem. 2017. PMID 27614217.
• "Hematopoietic prostaglandin D synthase defines a proeosinophilic pathogenic effector human T(H)2 cell subpopulation with enhanced function. ". J Allergy Clin Immunol. 2016. PMID 26431580.
• "Urinary prostaglandin D synthase as biomarker in lupus nephritis: a longitudinal study. ". Clin Exp Rheumatol. 2015. PMID 26211517.
• "Role of Lipocalin-type prostaglandin D2 synthase (L-PGDS) and its metabolite, prostaglandin D2, in preterm birth. ". Prostaglandins Other Lipid Mediat. 2015. PMID 25964109.
• "Lipocalin-type prostaglandin D synthase scavenges biliverdin in the cerebrospinal fluid of patients with aneurysmal subarachnoid hemorrhage.". J Cereb Blood Flow Metab. 2014. PMID 25005874.