PSMB7

PSMB7
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 4R3O, 4R67, 5A0Q
Dynodwyr
Cyfenwau	PSMB7, proteasome subunit beta 7, Z, proteasome 20S subunit beta 7
Dynodwyr allanol	OMIM: 604030 HomoloGene: 2093 GeneCards: PSMB7
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • endopeptidase activity • GO:0070122 peptidase activity • GO:0001948, GO:0016582 protein binding • threonine-type endopeptidase activity • hydrolase activity Cydrannau o'r gell • nucleoplasm • proteasome complex • extracellular exosome • cnewyllyn cell • proteasome core complex • extracellular region • cytoplasm • cytosol • secretory granule lumen • ficolin-1-rich granule lumen • proteasome core complex, beta-subunit complex Prosesau biolegol • regulation of cellular amino acid metabolic process • antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent • regulation of mRNA stability • positive regulation of protein targeting to mitochondrion • positive regulation of canonical Wnt signaling pathway • protein polyubiquitination • stimulatory C-type lectin receptor signaling pathway • tumor necrosis factor-mediated signaling pathway • MAPK cascade • proteolysis • Fc-epsilon receptor signaling pathway • NIK/NF-kappaB signaling • anaphase-promoting complex-dependent catabolic process • proteolysis involved in cellular protein catabolic process • T cell receptor signaling pathway • negative regulation of canonical Wnt signaling pathway • Wnt signaling pathway, planar cell polarity pathway • proteasome-mediated ubiquitin-dependent protein catabolic process • GO:0022415 viral process • negative regulation of G2/M transition of mitotic cell cycle • protein deubiquitination • SCF-dependent proteasomal ubiquitin-dependent protein catabolic process • neutrophil degranulation • transmembrane transport • regulation of transcription from RNA polymerase II promoter in response to hypoxia • post-translational protein modification • regulation of hematopoietic stem cell differentiation • proteasomal protein catabolic process • proteasomal ubiquitin-independent protein catabolic process • interleukin-1-mediated signaling pathway • regulation of mitotic cell cycle phase transition Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	5695	n/a
Ensembl	ENSG00000136930	n/a
UniProt	Q99436 Q5TBG5	n/a
RefSeq (mRNA)	NM_002799	n/a
RefSeq (protein)	NP_002790	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn PSMB7 yw PSMB7 a elwir hefyd yn Proteasome subunit beta type a Proteasome subunit beta 7 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 9, band 9q33.3.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn PSMB7.

• Z

Llyfryddiaeth

• "An unreported mutation within protein Z gene is associated with very low protein levels in women with fetal loss. ". Fertil Steril. 2008. PMID 18462727.
• "Regulation of proteasome complexes by gamma-interferon and phosphorylation. ". Biochimie. 2001. PMID 11295498.
• "Decreased proteinZ levels in patients with rheumatoid arthritis: links with inflammation. ". Thromb Haemost. 2011. PMID 21713324.
• "PSMB7 is associated with anthracycline resistance and is a prognostic biomarker in breast cancer. ". Br J Cancer. 2010. PMID 20010949.
• "Characterization and differential expression of a newly identified phosphorylated isoform of the human 20S proteasome beta7 subunit in tumor vs. normal cell lines.". Fundam Clin Pharmacol. 2009. PMID 19645816.