PSMB1

PSMB1
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 4R3O, 4R67, 5A0Q
Dynodwyr
Cyfenwau	PSMB1, HC5, PMSB1, PSC5, proteasome subunit beta 1, proteasome 20S subunit beta 1
Dynodwyr allanol	OMIM: 602017 HomoloGene: 2087 GeneCards: PSMB1
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • endopeptidase activity • GO:0070122 peptidase activity • GO:0001948, GO:0016582 protein binding • threonine-type endopeptidase activity • hydrolase activity Cydrannau o'r gell • cytoplasm • cytosol • nucleoplasm • proteasome complex • extracellular exosome • cnewyllyn cell • proteasome core complex • extracellular region • secretory granule lumen • ficolin-1-rich granule lumen • proteasome core complex, beta-subunit complex Prosesau biolegol • regulation of cellular amino acid metabolic process • antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent • regulation of mRNA stability • positive regulation of canonical Wnt signaling pathway • protein polyubiquitination • stimulatory C-type lectin receptor signaling pathway • tumor necrosis factor-mediated signaling pathway • MAPK cascade • proteolysis • Fc-epsilon receptor signaling pathway • NIK/NF-kappaB signaling • anaphase-promoting complex-dependent catabolic process • proteolysis involved in cellular protein catabolic process • T cell receptor signaling pathway • negative regulation of canonical Wnt signaling pathway • proteasome-mediated ubiquitin-dependent protein catabolic process • GO:0022415 viral process • Wnt signaling pathway, planar cell polarity pathway • negative regulation of G2/M transition of mitotic cell cycle • protein deubiquitination • SCF-dependent proteasomal ubiquitin-dependent protein catabolic process • neutrophil degranulation • transmembrane transport • regulation of transcription from RNA polymerase II promoter in response to hypoxia • post-translational protein modification • regulation of hematopoietic stem cell differentiation • proteasomal protein catabolic process • proteasomal ubiquitin-independent protein catabolic process • interleukin-1-mediated signaling pathway • regulation of mitotic cell cycle phase transition Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	5689	n/a
Ensembl	ENSG00000008018 ENSG00000281184	n/a
UniProt	P20618	n/a
RefSeq (mRNA)	NM_002793	n/a
RefSeq (protein)	NP_002784	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn PSMB1 yw PSMB1 a elwir hefyd yn Proteasome subunit beta 1 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 6, band 6q27.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn PSMB1.

• HC5
• PSC5
• PMSB1

Llyfryddiaeth

• "Prespecified candidate biomarkers identify follicular lymphoma patients who achieved longer progression-free survival with bortezomib-rituximab versus rituximab. ". Clin Cancer Res. 2013. PMID 23549871.
• "Interaction of plasminogen activator inhibitor-2 and proteasome subunit, beta type 1. ". Acta Biochim Biophys Sin (Shanghai). 2004. PMID 14732874.
• "Role of nuclear localization of PSMB1 in transcriptional activation. ". Biosci Biotechnol Biochem. 2013. PMID 23924720.
• "Gene expression of catalytic proteasome subunits and resistance toward proteasome inhibition of B lymphocytes from patients with primary sjogren syndrome. ". J Rheumatol. 2013. PMID 23504381.
• "[Influence of As(2)O(3) on proteasome beta(1)-subunit in NB4 cells].". Zhongguo Shi Yan Xue Ye Xue Za Zhi. 2009. PMID 19549367.