PSMA7

PSMA7
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 4R3O, 4R67, 1IRU, 5A0Q
Dynodwyr
Cyfenwau	PSMA7, C6, HSPC, RC6-1, XAPC7, HEL-S-276, proteasome subunit alpha 7, proteasome 20S subunit alpha 7
Dynodwyr allanol	OMIM: 606607 HomoloGene: 105299 GeneCards: PSMA7
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • endopeptidase activity • GO:0070122 peptidase activity • GO:0001948, GO:0016582 protein binding • identical protein binding • threonine-type endopeptidase activity • hydrolase activity Cydrannau o'r gell • cytoplasm • cytosol • nucleoplasm • proteasome complex • extracellular exosome • cnewyllyn cell • proteasome core complex • postsynapse • proteasome core complex, alpha-subunit complex Prosesau biolegol • regulation of cellular amino acid metabolic process • antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent • ubiquitin-dependent protein catabolic process • regulation of mRNA stability • positive regulation of canonical Wnt signaling pathway • protein polyubiquitination • stimulatory C-type lectin receptor signaling pathway • tumor necrosis factor-mediated signaling pathway • proteolysis • MAPK cascade • Fc-epsilon receptor signaling pathway • NIK/NF-kappaB signaling • anaphase-promoting complex-dependent catabolic process • proteolysis involved in cellular protein catabolic process • T cell receptor signaling pathway • negative regulation of canonical Wnt signaling pathway • proteasome-mediated ubiquitin-dependent protein catabolic process • GO:0022415 viral process • Wnt signaling pathway, planar cell polarity pathway • negative regulation of G2/M transition of mitotic cell cycle • protein deubiquitination • SCF-dependent proteasomal ubiquitin-dependent protein catabolic process • transmembrane transport • regulation of transcription from RNA polymerase II promoter in response to hypoxia • post-translational protein modification • regulation of hematopoietic stem cell differentiation • proteasomal protein catabolic process • proteasomal ubiquitin-independent protein catabolic process • interleukin-1-mediated signaling pathway • regulation of mitotic cell cycle phase transition Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	5688	n/a
Ensembl	ENSG00000101182	n/a
UniProt	O14818	n/a
RefSeq (mRNA)	NM_152255 NM_002792	n/a
RefSeq (protein)	NP_002783	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn PSMA7 yw PSMA7 a elwir hefyd yn Proteasome subunit alpha 7 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 20, band 20q13.33.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn PSMA7.

• C6
• HSPC
• RC6-1
• XAPC7
• HEL-S-276

Llyfryddiaeth

• "[High expression of proteasome subunit PSMA7 in colorectal cancer is significantly correlated with liver metastasis]. ". Zhonghua Zhong Liu Za Zhi. 2008. PMID 19062718.
• "The proteasome subunit PSMA7 located on the 20q13 amplicon is overexpressed and associated with liver metastasis in colorectal cancer. ". Oncol Rep. 2008. PMID 18202793.
• "Salivary exosomal PSMA7: a promising biomarker of inflammatory bowel disease. ". Protein Cell. 2017. PMID 28523434.
• "PSMA7 inhibits the tumorigenicity of A549 human lung adenocarcinoma cells. ". Mol Cell Biochem. 2012. PMID 22584585.
• "PSMA7, a potential biomarker of diseases.". Protein Pept Lett. 2009. PMID 19442227.