PSMA5

PSMA5
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 4R3O, 4R67, 3UNB, 3UNE, 3UNF, 3UNH, 5A0Q
Dynodwyr
Cyfenwau	PSMA5, PSC5, ZETA, proteasome subunit alpha 5, proteasome 20S subunit alpha 5
Dynodwyr allanol	OMIM: 176844 HomoloGene: 2084 GeneCards: PSMA5
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • endopeptidase activity • GO:0070122 peptidase activity • GO:0001948, GO:0016582 protein binding • threonine-type endopeptidase activity • hydrolase activity Cydrannau o'r gell • proteasome complex • extracellular exosome • cnewyllyn cell • proteasome core complex • extracellular region • nucleoplasm • cytoplasm • secretory granule lumen • ficolin-1-rich granule lumen • cytosol • proteasome core complex, alpha-subunit complex Prosesau biolegol • regulation of cellular amino acid metabolic process • antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent • ubiquitin-dependent protein catabolic process • regulation of mRNA stability • positive regulation of canonical Wnt signaling pathway • protein polyubiquitination • stimulatory C-type lectin receptor signaling pathway • tumor necrosis factor-mediated signaling pathway • proteolysis • MAPK cascade • Fc-epsilon receptor signaling pathway • NIK/NF-kappaB signaling • anaphase-promoting complex-dependent catabolic process • proteolysis involved in cellular protein catabolic process • T cell receptor signaling pathway • negative regulation of canonical Wnt signaling pathway • Wnt signaling pathway, planar cell polarity pathway • negative regulation of G2/M transition of mitotic cell cycle • protein deubiquitination • SCF-dependent proteasomal ubiquitin-dependent protein catabolic process • proteasome-mediated ubiquitin-dependent protein catabolic process • neutrophil degranulation • transmembrane transport • regulation of transcription from RNA polymerase II promoter in response to hypoxia • post-translational protein modification • regulation of hematopoietic stem cell differentiation • proteasomal protein catabolic process • proteasomal ubiquitin-independent protein catabolic process • interleukin-1-mediated signaling pathway • regulation of mitotic cell cycle phase transition Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	5686	n/a
Ensembl	ENSG00000143106	n/a
UniProt	P28066	n/a
RefSeq (mRNA)	NM_002790 NM_001199772 NM_001199773 NM_001199774	n/a
RefSeq (protein)	NP_001186701 NP_001186702 NP_001186703 NP_002781	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn PSMA5 yw PSMA5 a elwir hefyd yn Proteasome subunit alpha 5 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 1, band 1p13.3.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn PSMA5.

• PSC5
• ZETA

Llyfryddiaeth

• "Defective Proteasome Delivery of Polyubiquitinated Proteins by Ubiquilin-2 Proteins Containing ALS Mutations. ". PLoS One. 2015. PMID 26075709.
• "Direct proteasome binding and subsequent degradation of unspliced XBP-1 prevent its intracellular aggregation. ". FEBS Lett. 2010. PMID 19941857.
• "Proteasome subunit zeta, a putative ribonuclease, is also found as a free monomer. ". Mol Biol Rep. 1999. PMID 10363657.
• "Twelve genes, including the unassigned proteasome zeta subunit gene, ordered within the human 1p13 region. ". Mamm Genome. 1998. PMID 9530635.
• "Selective upregulation of the ubiquitin-proteasome proteolytic pathway proteins, proteasome zeta chain and isopeptidase T in fetal Down syndrome.". J Neural Transm Suppl. 2001. PMID 11771738.