PSMA2

PSMA2
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 4R3O, 4R67, 5A0Q
Dynodwyr
Cyfenwau	PSMA2, HC3, MU, PMSA2, PSC2, proteasome subunit alpha 2, proteasome 20S subunit alpha 2
Dynodwyr allanol	OMIM: 176842 HomoloGene: 2081 GeneCards: PSMA2
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • endopeptidase activity • GO:0070122 peptidase activity • GO:0001948, GO:0016582 protein binding • threonine-type endopeptidase activity • hydrolase activity Cydrannau o'r gell • cytoplasm • cytosol • nucleoplasm • proteasome complex • extracellular exosome • cnewyllyn cell • proteasome core complex • extracellular region • secretory granule lumen • ficolin-1-rich granule lumen • proteasome core complex, alpha-subunit complex • P-body Prosesau biolegol • regulation of cellular amino acid metabolic process • antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent • regulation of mRNA stability • ubiquitin-dependent protein catabolic process • positive regulation of canonical Wnt signaling pathway • response to virus • protein polyubiquitination • stimulatory C-type lectin receptor signaling pathway • tumor necrosis factor-mediated signaling pathway • proteolysis • MAPK cascade • Fc-epsilon receptor signaling pathway • NIK/NF-kappaB signaling • anaphase-promoting complex-dependent catabolic process • proteolysis involved in cellular protein catabolic process • T cell receptor signaling pathway • negative regulation of canonical Wnt signaling pathway • proteasome-mediated ubiquitin-dependent protein catabolic process • Wnt signaling pathway, planar cell polarity pathway • negative regulation of G2/M transition of mitotic cell cycle • protein deubiquitination • SCF-dependent proteasomal ubiquitin-dependent protein catabolic process • neutrophil degranulation • transmembrane transport • regulation of transcription from RNA polymerase II promoter in response to hypoxia • post-translational protein modification • regulation of hematopoietic stem cell differentiation • proteasomal protein catabolic process • proteasomal ubiquitin-independent protein catabolic process • interleukin-1-mediated signaling pathway • regulation of mitotic cell cycle phase transition Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	5683	n/a
Ensembl	ENSG00000106588	n/a
UniProt	P25787	n/a
RefSeq (mRNA)	NM_002787	n/a
RefSeq (protein)	NP_002778	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn PSMA2 yw PSMA2 a elwir hefyd yn Proteasome subunit alpha 2 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 7, band 7p14.1.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn PSMA2.

• MU
• HC3
• PSC2
• PMSA2

Llyfryddiaeth

• "Functional analysis of eukaryotic 20S proteasome nuclear localization signal. ". Exp Cell Res. 1996. PMID 8635518.
• "Isolation and characterization of alpha-type HC3 and beta-type HC5 subunit genes of human proteasomes. ". J Mol Biol. 1994. PMID 7966316.
• "[Expression of genes psma6 and slc25a4 in patients with acute monocytic leukemia]. ". Zhongguo Shi Yan Xue Ye Xue Za Zhi. 2009. PMID 19840444.
• "Mechanism of direct degradation of IkappaBalpha by 20S proteasome. ". FEBS Lett. 2005. PMID 16098527.
• "The ubiquitin-associated domain of hPLIC-2 interacts with the proteasome.". Mol Biol Cell. 2003. PMID 12972570.