PRPF40A

PRPF40A
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1UZC, 1YWI, 1YWJ, 1ZR7, 2CQN, 2DYF, 2KZG, 2L5F, 2L9V, 2LKS
Dynodwyr
Cyfenwau	PRPF40A, FBP-11, FBP11, FLAF1, FNBP3, HIP-10, HIP10, HYPA, NY-REN-6, Prp40, pre-mRNA processing factor 40 homolog A
Dynodwyr allanol	OMIM: 612941 HomoloGene: 6377 GeneCards: PRPF40A
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • proline-rich region binding • GO:0001948, GO:0016582 protein binding • RNA binding Cydrannau o'r gell • nuclear matrix • U1 snRNP • U2-type prespliceosome • bilen • cnewyllyn cell • nucleoplasm • cytosol • nuclear speck Prosesau biolegol • Cellraniad • cell cycle • mRNA processing • regulation of cytokinesis • cell migration • cytoskeleton organization • RNA splicing • regulation of cell shape • mRNA splicing, via spliceosome • mRNA cis splicing, via spliceosome Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	55660	n/a
Ensembl	ENSG00000196504	n/a
UniProt	O75400	n/a
RefSeq (mRNA)	NM_017892 NM_001354432 NM_001354431 NM_001365596 NM_001365597 NM_001365598 NM_001365599 NM_001365600 NM_001365601 NM_001365602 NM_001365603 NM_001365604 NM_001365605 NM_001395472 NM_001395473 NM_001395475 NM_001395476 NM_001395477 NM_001395478 NM_001395479 NM_001395480 NM_001395481 NM_001395482 NM_001395483 NM_001395488	n/a
RefSeq (protein)	NP_060362 NP_001341361 NP_001341360 NP_001352525 NP_001352526 NP_001352527 NP_001352528 NP_001352529 NP_001352530 NP_001352531 NP_001352532 NP_001352533 NP_001352534	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn PRPF40A yw PRPF40A a elwir hefyd yn Pre-mRNA processing factor 40 homolog A (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 2, band 2q23.3.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn PRPF40A.

• HYPA
• FBP11
• FLAF1
• FNBP3
• HIP10
• Prp40
• FBP-11
• HIP-10
• NY-REN-6

Llyfryddiaeth

• "Solution structure and ligand recognition of the WW domain pair of the yeast splicing factor Prp40. ". J Mol Biol. 2002. PMID 12460579.
• "Interaction with polyglutamine-expanded huntingtin alters cellular distribution and RNA processing of huntingtin yeast two-hybrid protein A (HYPA). ". J Biol Chem. 2011. PMID 21566141.
• "The effect of C-terminal helix on the stability of FF domain studied by molecular dynamics simulation. ". Int J Mol Sci. 2012. PMID 22408419.
• "A transient and low-populated protein-folding intermediate at atomic resolution. ". Science. 2010. PMID 20829478.
• "Structure of FBP11 WW1-PL ligand complex reveals the mechanism of proline-rich ligand recognition by group II/III WW domains.". J Biol Chem. 2006. PMID 17065151.