PROS1

PROS1
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1Z6C
Dynodwyr
Cyfenwau	PROS1, PROS, PS21, PS22, PS23, PS24, PS25, PSA, THPH5, THPH6, protein S (alpha), protein S
Dynodwyr allanol	OMIM: 176880 HomoloGene: 264 GeneCards: PROS1
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • calcium ion binding • endopeptidase inhibitor activity Cydrannau o'r gell • blood microparticle • endoplasmic reticulum membrane • Golgi membrane • Cellbilen • extracellular region • Golgi lumen • extracellular exosome • platelet alpha granule lumen • extracellular space Prosesau biolegol • hemostasis • fibrinolysis • platelet degranulation • blood coagulation • endoplasmic reticulum to Golgi vesicle-mediated transport • signal peptide processing • peptidyl-glutamic acid carboxylation • regulation of complement activation • leukocyte migration • negative regulation of endopeptidase activity • negative regulation of blood coagulation Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	5627	n/a
Ensembl	ENSG00000184500	n/a
UniProt	P07225	n/a
RefSeq (mRNA)	NM_000313 NM_001314077	n/a
RefSeq (protein)	NP_000304 NP_001301006	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn PROS1 yw PROS1 a elwir hefyd yn Protein S (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 3, band 3q11.1.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn PROS1.

• PSA
• PROS
• PS21
• PS22
• PS23
• PS24
• PS25
• THPH5
• THPH6

Llyfryddiaeth

• "A fluorogenic probe for imaging protein S-nitrosylation in live cells. ". Biosens Bioelectron. 2017. PMID 28284075.
• "Genotyping analysis of protein S-Tokushima (K196E) and the involvement of protein S antigen and activity in patients with recurrent pregnancy loss. ". Eur J Obstet Gynecol Reprod Biol. 2017. PMID 28214760.
• "Gene analysis of six cases of congenital protein S deficiency and functional analysis of protein S mutations (A139V, C449F, R451Q, C475F, A525V and D599TfsTer13). ". Thromb Res. 2017. PMID 28088608.
• "A novel PROS1 mutation, c.74dupA, was identified in a protein S deficiency family. ". Thromb Res. 2016. PMID 27846449.
• "Silencing of PROS1 induces apoptosis and inhibits migration and invasion of glioblastoma multiforme cells.". Int J Oncol. 2016. PMID 27840905.