PRKAG1

PRKAG1
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2UV4, 2UV5, 2UV6, 2UV7, 4CFE, 4CFF, 4RER, 4REW, 5EZV, 4ZHX
Dynodwyr
Cyfenwau	PRKAG1, AMPKG, protein kinase AMP-activated non-catalytic subunit gamma 1
Dynodwyr allanol	OMIM: 602742 HomoloGene: 99712 GeneCards: PRKAG1
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • nucleotide binding • protein kinase activity • cAMP-dependent protein kinase activity • ADP binding • AMP-activated protein kinase activity • AMP binding • GO:0001948, GO:0016582 protein binding • cAMP-dependent protein kinase regulator activity • protein kinase binding • ATP binding • adenyl ribonucleotide binding Cydrannau o'r gell • cytosol • bilen • nucleotide-activated protein kinase complex • extracellular exosome • cnewyllyn cell • nucleoplasm Prosesau biolegol • lipid metabolism • fatty acid metabolic process • regulation of glycolytic process • protein phosphorylation • GO:1901313 positive regulation of gene expression • fatty acid biosynthetic process • spermatogenesis • macroautophagy • GO:0072468 signal transduction • positive regulation of protein kinase activity • regulation of signal transduction by p53 class mediator • regulation of macroautophagy • import into nucleus • regulation of protein serine/threonine kinase activity Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	5571	n/a
Ensembl	ENSG00000181929	n/a
UniProt	P54619	n/a
RefSeq (mRNA)	NM_001206709 NM_001206710 NM_002733 NM_212461	n/a
RefSeq (protein)	NP_001193638 NP_001193639 NP_002724	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn PRKAG1 yw PRKAG1 a elwir hefyd yn Protein kinase AMP-activated non-catalytic subunit gamma 1 a 5'-AMP-activated protein kinase subunit gamma-1 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 12, band 12q13.12.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn PRKAG1.

• AMPKG

Llyfryddiaeth

• "Inhibition of the KCa3.1 channels by AMP-activated protein kinase in human airway epithelial cells. ". Am J Physiol Cell Physiol. 2009. PMID 19052260.
• "AMP-activated protein kinase subunit interactions: beta1:gamma1 association requires beta1 Thr-263 and Tyr-267. ". J Biol Chem. 2008. PMID 18079111.
• "Frameshift mutations of PRKAG1 gene encoding an AMPK gamma subunit in colorectal cancers. ". J Gastrointestin Liver Dis. 2014. PMID 25267969.
• "Prolyl isomerase Pin1 negatively regulates AMP-activated protein kinase (AMPK) by associating with the CBS domain in the γ subunit. ". J Biol Chem. 2015. PMID 26276391.
• "AMPK interacts with DSCAM and plays an important role in netrin-1 induced neurite outgrowth.". Protein Cell. 2013. PMID 23479427.