PRG4

PRG4
Dynodwyr
Cyfenwau	PRG4, CACP, HAPO, JCAP, MSF, SZP, bG174L6.2, proteoglycan 4
Dynodwyr allanol	OMIM: 604283 HomoloGene: 130465 GeneCards: PRG4
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • scavenger receptor activity • polysaccharide binding • extracellular matrix structural constituent conferring compression resistance Cydrannau o'r gell • extracellular region • GO:0005578 extracellular matrix • collagen-containing extracellular matrix Prosesau biolegol • cell population proliferation • receptor-mediated endocytosis • GO:0046730, GO:0046737, GO:0046738, GO:0046736 immune response • vesicle-mediated transport • endocytosis Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	10216	n/a
Ensembl	ENSG00000116690	n/a
UniProt	Q92954	n/a
RefSeq (mRNA)	NM_005807 NM_001127708 NM_001127709 NM_001127710 NM_001303232	n/a
RefSeq (protein)	NP_001121180 NP_001121181 NP_001121182 NP_001290161 NP_005798	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn PRG4 yw PRG4 a elwir hefyd yn Proteoglycan 4 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 1, band 1q31.1.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn PRG4.

• MSF
• SZP
• CACP
• HAPO
• JCAP

Llyfryddiaeth

• "Does intra-articular fracture change the lubricant content of synovial fluid?". J Orthop Surg Res. 2015. PMID 26037740.
• "Biosynthesis of collagen I, II, RUNX2 and lubricin at different time points of chondrogenic differentiation in a 3D in vitro model of human mesenchymal stem cells derived from adipose tissue. ". Acta Histochem. 2014. PMID 25307495.
• "PRG4 expression in myxoid liposarcoma maintains tumor cell growth through suppression of an antitumor cytokine IL-24. ". Biochem Biophys Res Commun. 2017. PMID 28192118.
• "Implications of trauma and subsequent articulation on the release of Proteoglycan-4 and tissue response in adult human ankle cartilage. ". J Orthop Res. 2017. PMID 27551813.
• "Abundant lubricin expression suggests a link between synoviocytes, synovial tumors, and myxomas.". Histol Histopathol. 2016. PMID 26924731.