PRDX6

PRDX6
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1PRX, 5B6N, 5B6M
Dynodwyr
Cyfenwau	PRDX6, 1-Cys, AOP2, HEL-S-128m, NSGPx, PRX, aiPLA2, p29, peroxiredoxin 6, LPCAT-5
Dynodwyr allanol	OMIM: 602316 HomoloGene: 3606 GeneCards: PRDX6
EC number	1.11.1.9
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • peroxidase activity • catalytic activity • GO:0001948, GO:0016582 protein binding • peroxiredoxin activity • oxidoreductase activity • hydrolase activity • ubiquitin protein ligase binding • antioxidant activity • cadherin binding • glutathione peroxidase activity • protein homodimerization activity • calcium-independent phospholipase A2 activity • phospholipase A2 activity Cydrannau o'r gell • cytoplasm • cytosol • bilen • lysosome • extracellular exosome • extracellular region • extracellular space • azurophil granule lumen • cnewyllyn cell • perinuclear region of cytoplasm Prosesau biolegol • lipid metabolism • lipid catabolic process • hydrogen peroxide catabolic process • metabolaeth • cell redox homeostasis • neutrophil degranulation • GO:0001306 response to oxidative stress • cellular response to oxidative stress • glycerophospholipid catabolic process • cellular oxidant detoxification • positive regulation of mRNA splicing, via spliceosome Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	9588	n/a
Ensembl	ENSG00000117592	n/a
UniProt	P30041	n/a
RefSeq (mRNA)	NM_004905	n/a
RefSeq (protein)	NP_004896	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn PRDX6 yw PRDX6 a elwir hefyd yn Peroxiredoxin 6 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 1, band 1q25.1.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn PRDX6.

• PRX
• p29
• AOP2
• 1-Cys
• NSGPx
• aiPLA2
• HEL-S-128m

Llyfryddiaeth

• "Crystal structures of human peroxiredoxin 6 in different oxidation states. ". Biochem Biophys Res Commun. 2016. PMID 27353378.
• "Peroxiredoxin 6 attenuates ischemia‑ and hypoxia‑induced liver damage of brain‑dead donors. ". Mol Med Rep. 2016. PMID 26647763.
• "Peroxiredoxin-6 Negatively Regulates Bactericidal Activity and NF-κB Activity by Interrupting TRAF6-ECSIT Complex. ". Front Cell Infect Microbiol. 2017. PMID 28393051.
• "Proteomic profiling of fetal esophageal epithelium, esophageal cancer, and tumor-adjacent esophageal epithelium and immunohistochemical characterization of a representative differential protein, PRX6. ". World J Gastroenterol. 2017. PMID 28293090.
• "Peroxiredoxin 6 in the repair of peroxidized cell membranes and cell signaling.". Arch Biochem Biophys. 2017. PMID 27932289.