PRDX4

PRDX4
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2PN8, 3TJB, 3TJF, 3TJG, 3TJJ, 3TJK, 3TKP, 3TKQ, 3TKR, 3TKS, 4RQX
Dynodwyr
Cyfenwau	PRDX4, AOE37-2, AOE372, HEL-S-97n, PRX-4, peroxiredoxin 4
Dynodwyr allanol	OMIM: 300927 HomoloGene: 4672 GeneCards: PRDX4
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • protein homodimerization activity • peroxidase activity • thioredoxin peroxidase activity • antioxidant activity • GO:0001948, GO:0016582 protein binding • peroxiredoxin activity • oxidoreductase activity Cydrannau o'r gell • cytoplasm • cytosol • smooth endoplasmic reticulum • Reticwlwm endoplasmig • mitocondria • extracellular exosome • cnewyllyn cell • extracellular space • secretory granule lumen • ficolin-1-rich granule lumen • extracellular region Prosesau biolegol • male gonad development • 4-hydroxyproline metabolic process • extracellular matrix organization • I-kappaB phosphorylation • protein maturation by protein folding • cell redox homeostasis • reactive oxygen species metabolic process • spermatogenesis • negative regulation of male germ cell proliferation • cellular oxidant detoxification • neutrophil degranulation • GO:0001306 response to oxidative stress • hydrogen peroxide catabolic process Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	10549	n/a
Ensembl	ENSG00000123131	n/a
UniProt	Q13162	n/a
RefSeq (mRNA)	NM_006406	n/a
RefSeq (protein)	NP_006397	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn PRDX4 yw PRDX4 a elwir hefyd yn Peroxiredoxin-4 a Peroxiredoxin 4 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom X dynol, band Xp22.11.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn PRDX4.

• PRX-4
• AOE372
• AOE37-2
• HEL-S-97n

Llyfryddiaeth

• "Peroxiredoxin 4 improves insulin biosynthesis and glucose-induced insulin secretion in insulin-secreting INS-1E cells. ". J Biol Chem. 2014. PMID 25122762.
• "Circulating peroxiredoxin 4 and type 2 diabetes risk: the Prevention of Renal and Vascular Endstage Disease (PREVEND) study. ". Diabetologia. 2014. PMID 24893865.
• "Increased peroxiredoxin 4 levels in patients with prediabetes compared to normal glucose tolerance subjects. ". Clin Endocrinol (Oxf). 2016. PMID 27303935.
• "Peroxiredoxin 4 as an independent prognostic marker for survival in patients with early-stage lung squamous cell carcinoma. ". Int J Clin Exp Pathol. 2015. PMID 26261544.
• "A novel reaction of peroxiredoxin 4 towards substrates in oxidative protein folding.". PLoS One. 2014. PMID 25137134.