PRC1

PRC1
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 3NRX, 3NRY, 4L3I, 4L6Y
Dynodwyr
Cyfenwau	PRC1, ASE1, protein regulator of cytokinesis 1
Dynodwyr allanol	OMIM: 603484 HomoloGene: 37868 GeneCards: PRC1
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • protein kinase binding • identical protein binding • kinesin binding • microtubule binding • GO:0001948, GO:0016582 protein binding Cydrannau o'r gell • spindle • cytosol • spindle pole • microtubule • spindle microtubule • contractile ring • Cytosgerbwd • cnewyllyn cell • midbody • cytoplasm Prosesau biolegol • microtubule bundle formation • cell cycle • Cellraniad • microtubule cytoskeleton organization • mitotic spindle elongation • positive regulation of cell population proliferation • cytokinesis • regulation of cytokinesis Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	9055	n/a
Ensembl	ENSG00000198901	n/a
UniProt	O43663	n/a
RefSeq (mRNA)	NM_001267580 NM_003981 NM_199413 NM_199414	n/a
RefSeq (protein)	NP_001254509 NP_003972 NP_955445	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn PRC1 yw PRC1 a elwir hefyd yn Protein regulator of cytokinesis 1 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 15, band 15q26.1.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn PRC1.

• ASE1

Llyfryddiaeth

• "The BEG (PP2A-B55/ENSA/Greatwall) pathway ensures cytokinesis follows chromosome separation. ". Mol Cell. 2013. PMID 24120663.
• "Nonredundant and locus-specific gene repression functions of PRC1 paralog family members in human hematopoietic stem/progenitor cells. ". Blood. 2013. PMID 23349393.
• "Genetic and functional analyses do not explain the association of high PRC1 expression with poor survival of breast carcinoma patients. ". Biomed Pharmacother. 2016. PMID 27505863.
• "The microtubule-associated protein PRC1 promotes early recurrence of hepatocellular carcinoma in association with the Wnt/β-catenin signalling pathway. ". Gut. 2016. PMID 26941395.
• "Protein regulator of cytokinesis 1 overexpression predicts biochemical recurrence in men with prostate cancer.". Biomed Pharmacother. 2016. PMID 26898432.