PPP5C

PPP5C
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1A17, 1S95, 1WAO, 2BUG, 3H60, 3H61, 3H62, 3H63, 3H64, 3H66, 3H67, 3H68, 3H69, 4ZX2, 4ZVZ
Dynodwyr
Cyfenwau	PPP5C, PP5, PPP5, PPT, protein phosphatase 5 catalytic subunit
Dynodwyr allanol	OMIM: 600658 HomoloGene: 4550 GeneCards: PPP5C
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • phosphoprotein phosphatase activity • heat shock protein binding • microtubule binding • ADP binding • protein serine/threonine phosphatase activity • signal transducer activity • metal ion binding • GO:0001948, GO:0016582 protein binding • RNA binding • identical protein binding • G-protein alpha-subunit binding • hydrolase activity • ATP binding • lipid binding • Hsp90 protein binding Cydrannau o'r gell • perikaryon • bilen • intracellular membrane-bounded organelle • Cellbilen • neuronal cell body • proximal dendrite • neuron projection • cnewyllyn cell • cyrion cell • nucleoplasm • cytoplasm • cytosol Prosesau biolegol • GO:0033128 negative regulation of protein phosphorylation • positive regulation of glucocorticoid receptor signaling pathway • protein heterooligomerization • GO:0016576 protein dephosphorylation • negative regulation of cell death • cellular response to cadmium ion • transcription, DNA-templated • MAPK cascade • cellular response to DNA damage stimulus • response to morphine • response to lead ion • protein complex oligomerization • positive regulation of I-kappaB kinase/NF-kappaB signaling • cellular response to hydrogen peroxide • negative regulation of neuron death • GO:0100026 DNA repair • GO:0007067 Mitosis Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	5536	n/a
Ensembl	ENSG00000011485	n/a
UniProt	P53041	n/a
RefSeq (mRNA)	NM_006247 NM_001204284	n/a
RefSeq (protein)	NP_001191213 NP_006238	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn PPP5C yw PPP5C a elwir hefyd yn Protein phosphatase 5 catalytic subunit (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 19, band 19q13.32.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn PPP5C.

• PP5
• PPT
• PPP5

Llyfryddiaeth

• "Serine/Threonine Protein Phosphatase-5 Accelerates Cell Growth and Migration in Human Glioma. ". Cell Mol Neurobiol. 2015. PMID 25796168.
• "Knockdown of PPP5C inhibits growth of hepatocellular carcinoma cells in vitro. ". Appl Biochem Biotechnol. 2015. PMID 25326185.
• "Cytokine-Induced Glucocorticoid Resistance from Eosinophil Activation: Protein Phosphatase 5 Modulation of Glucocorticoid Receptor Phosphorylation and Signaling. ". J Immunol. 2016. PMID 27742828.
• "Protein phosphatase 5 mediates corticosteroid insensitivity in airway smooth muscle in patients with severe asthma. ". Allergy. 2017. PMID 27501780.
• "Measles Virus Infection Inactivates Cellular Protein Phosphatase 5 with Consequent Suppression of Sp1 and c-Myc Activities.". J Virol. 2015. PMID 26157124.