PPP1R9B

PPP1R9B
Dynodwyr
Cyfenwau	PPP1R9B, PPP1R6, PPP1R9, SPINO, Spn, protein phosphatase 1 regulatory subunit 9B
Dynodwyr allanol	OMIM: 603325 HomoloGene: 32787 GeneCards: PPP1R9B
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • protein phosphatase 1 binding • GO:0001948, GO:0016582 protein binding • protein phosphatase inhibitor activity • actin binding • actin filament binding Cydrannau o'r gell • cytoplasm • cell projection • bilen • filopodium • adherens junction • Cellbilen • dendritic spine • synapse • nucleoplasm • ruffle membrane • cell junction • protein phosphatase type 1 complex • Cytosgerbwd • cnewyllyn cell • lamellipodium • GO:0097483, GO:0097481 postsynaptic density • actin cytoskeleton • dendrite Prosesau biolegol • cell differentiation • regulation of opioid receptor signaling pathway • filopodium assembly • regulation of cell growth by extracellular stimulus • modulation of chemical synaptic transmission • nervous system development • multicellular organism development • regulation of cell population proliferation • negative regulation of cell growth • RNA splicing • cellular response to morphine • cell migration • regulation of exit from mitosis • negative regulation of phosphoprotein phosphatase activity • actin filament organization • calcium-mediated signaling • neuron projection development Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	84687	n/a
Ensembl	ENSG00000108819	n/a
UniProt	Q96SB3	n/a
RefSeq (mRNA)	NM_032595	n/a
RefSeq (protein)	NP_115984	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn PPP1R9B yw PPP1R9B a elwir hefyd yn Protein phosphatase 1 regulatory subunit 9B (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 17, band 17q21.33.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn PPP1R9B.

• Spn
• SPINO
• PPP1R6
• PPP1R9

Llyfryddiaeth

• "Low spinophilin expression enhances aggressive biological behavior of breast cancer. ". Oncotarget. 2015. PMID 25857299.
• "Spinophilin expression determines cellular growth, cancer stemness and 5-flourouracil resistance in colorectal cancer. ". Oncotarget. 2014. PMID 25261368.
• "Effective Attenuation of Adenosine A1R Signaling by Neurabin Requires Oligomerization of Neurabin. ". Mol Pharmacol. 2017. PMID 28954816.
• "Loss of precuneus dendritic spines immunopositive for spinophilin is related to cognitive impairment in early Alzheimer's disease. ". Neurobiol Aging. 2017. PMID 28259365.
• "Loss of the tumor suppressor spinophilin (PPP1R9B) increases the cancer stem cell population in breast tumors.". Oncogene. 2016. PMID 26387546.