POU2F3

POU2F3
Dynodwyr
Cyfenwau	POU2F3, Epoc-1, OCT-11, OCT11, OTF-11, PLA-1, PLA1, Skn-1a, POU class 2 homeobox 3
Dynodwyr allanol	OMIM: 607394 HomoloGene: 7898 GeneCards: POU2F3
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • GO:0000980 RNA polymerase II cis-regulatory region sequence-specific DNA binding • GO:0001131, GO:0001151, GO:0001130, GO:0001204 DNA-binding transcription factor activity • sequence-specific DNA binding • DNA binding • GO:0001077, GO:0001212, GO:0001213, GO:0001211, GO:0001205 DNA-binding transcription activator activity, RNA polymerase II-specific • GO:0001948, GO:0016582 protein binding • GO:0001200, GO:0001133, GO:0001201 DNA-binding transcription factor activity, RNA polymerase II-specific Cydrannau o'r gell • cnewyllyn cell Prosesau biolegol • GO:0009373 regulation of transcription, DNA-templated • transcription, DNA-templated • GO:0003257, GO:0010735, GO:1901228, GO:1900622, GO:1904488 positive regulation of transcription by RNA polymerase II • transcription by RNA polymerase II • GO:0044324, GO:0003256, GO:1901213, GO:0046019, GO:0046020, GO:1900094, GO:0061216, GO:0060994, GO:1902064, GO:0003258, GO:0072212 regulation of transcription by RNA polymerase II • epidermis development Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	25833	n/a
Ensembl	ENSG00000137709	n/a
UniProt	Q9UKI9	n/a
RefSeq (mRNA)	NM_001244682 NM_014352	n/a
RefSeq (protein)	NP_001231611 NP_055167	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn POU2F3 yw POU2F3 a elwir hefyd yn POU class 2 homeobox 3 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 11, band 11q23.3.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn POU2F3.

• PLA1
• OCT11
• PLA-1
• Epoc-1
• OCT-11
• OTF-11
• Skn-1a

Llyfryddiaeth

• "Identification of Skn-1n, a splice variant induced by high calcium concentration and specifically expressed in normal human keratinocytes. ". J Invest Dermatol. 2008. PMID 17989732.
• "Aberrant promoter methylation and silencing of the POU2F3 gene in cervical cancer. ". Oncogene. 2006. PMID 16607278.
• "Functional analysis of the nuclear localization signal of the POU transcription factor Skn‑1a in epidermal keratinocytes. ". Int J Mol Med. 2014. PMID 24954220.
• "Relation between the expression levels of the POU transcription factors Skn-1a and Skn-1n and keratinocyte differentiation. ". J Dermatol Sci. 2010. PMID 21074976.
• "Transcription factor human Skn-1a enhances replication of human papillomavirus DNA through the direct binding to two sites near the viral replication origin.". FEBS J. 2008. PMID 18479461.