POLR2F

POLR2F
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1QKL, 5FLM, 5IY9, 5IYA, 5IYC, 5IYB, 5IY7, 5IY8, 5IYD, 5IY6
Dynodwyr
Cyfenwau	POLR2F, HRBP14.4, POLRF, RPABC14.4, RPABC2, RPB14.4, RPB6, RPC15, polymerase (RNA) II subunit F, RNA polymerase II subunit F, RNA polymerase II, I and III subunit F
Dynodwyr allanol	OMIM: 604414 HomoloGene: 7178 GeneCards: POLR2F
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • DNA binding • RNA polymerase II activity • RNA polymerase III activity • DNA-directed 5'-3' RNA polymerase activity • RNA polymerase I activity Cydrannau o'r gell • cytosol • nucleoplasm • RNA polymerase I complex • RNA polymerase III complex • RNA polymerase II, core complex • cnewyllyn cell • fibrillar center Prosesau biolegol • termination of RNA polymerase I transcription • mRNA splicing, via spliceosome • epigenetic maintenance of chromatin in transcription-competent conformation • transcription initiation from RNA polymerase I promoter • transcription elongation from RNA polymerase II promoter • 7-methylguanosine mRNA capping • transcription by RNA polymerase II • transcription-coupled nucleotide-excision repair • transcription initiation from RNA polymerase II promoter • snRNA transcription by RNA polymerase II • fibroblast growth factor receptor signaling pathway • transcription by RNA polymerase III • RNA metabolic process • GO:1905616 regulation of gene silencing by miRNA • transcription, DNA-templated • GO:0001183 transcription elongation from RNA polymerase I promoter • positive regulation of type I interferon production • somatic stem cell population maintenance • positive regulation of viral transcription Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	5435	n/a
Ensembl	ENSG00000100142	n/a
UniProt	P61218	n/a
RefSeq (mRNA)	NM_001301129 NM_001301130 NM_001301131 NM_021974 NM_001363825	n/a
RefSeq (protein)	NP_001288058 NP_001288059 NP_001288060 NP_068809 NP_001350754	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn POLR2F yw POLR2F a elwir hefyd yn RNA polymerase II subunit F (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 22, band 22q13.1.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn POLR2F.

• RPB6
• POLRF
• RPC15
• RPABC2
• RPB14.4
• HRBP14.4
• RPABC14.4

Llyfryddiaeth

• "Human RNA polymerase II-associated protein 2 (RPAP2) interacts directly with the RNA polymerase II subunit Rpb6 and participates in pre-mRNA 3'-end formation. ". Drug Discov Ther. 2014. PMID 25639305.
• "A serine residue in the N-terminal acidic region of rat RPB6, one of the common subunits of RNA polymerases, is exclusively phosphorylated by casein kinase II in vitro. ". Gene. 1999. PMID 10393248.
• "Solution structure of the hRPABC14.4 subunit of human RNA polymerases. ". Nat Struct Biol. 1999. PMID 10542096.
• "Genomic structure of the RNA polymerase II small subunit (hRPB14.4) locus (POLRF) and mapping to 22q13.1 by sequence identity. ". Genomics. 1996. PMID 8786150.
• "A 14.4 KDa acidic subunit of human RNA polymerase II with a putative leucine-zipper.". DNA Seq. 1994. PMID 7803819.