PMS1

PMS1
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2CS1
Dynodwyr
Cyfenwau	PMS1, HNPCC3, PMSL1, hMLH2, PMS1 homolog 1, mismatch repair system component
Dynodwyr allanol	OMIM: 600258 HomoloGene: 449 GeneCards: PMS1
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • single-stranded DNA binding • DNA binding • ATP binding • mismatched DNA binding • ATPase activity • enzyme binding Cydrannau o'r gell • MutLalpha complex • cnewyllyn cell • mismatch repair complex Prosesau biolegol • GO:0100026 DNA repair • cellular response to DNA damage stimulus • DNA mismatch repair Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	5378	n/a
Ensembl	ENSG00000064933	n/a
UniProt	P54277 Q5FBZ4	n/a
RefSeq (mRNA)	NM_000534 NM_001128143 NM_001128144 NM_001289408 NM_001289409 NM_001321044 NM_001321045 NM_001321046 NM_001321047 NM_001321048 NM_001321049 NM_001321051	n/a
RefSeq (protein)	NP_000525 NP_001121615 NP_001121616 NP_001276337 NP_001276338 NP_001307973 NP_001307974 NP_001307975 NP_001307976 NP_001307977 NP_001307978 NP_001307980	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn PMS1 yw PMS1 a elwir hefyd yn PMS1 nirs variant 6 a PMS1 homolog 1, mismatch repair system component (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 2, band 2q32.2.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn PMS1.

• MLH2
• PMSL1
• hPMS1
• HNPCC3

Llyfryddiaeth

• "Assignment of the human postmeiotic segregation increased (S. cerevisiae) 1 (PMS1) to chromosome 2q31.1 by radiation hybrid mapping. ". Cytogenet Cell Genet. 2000. PMID 10828585.
• "Expression of DNA mismatch repair genes in naevi. ". In Vivo. 1999. PMID 10459502.
• "The mismatch repair gene hPMS1 (human postmeiotic segregation1) is down regulated in oral squamous cell carcinoma. ". Gene. 2013. PMID 23608172.
• "Altered expression of mismatch repair proteins associated with acquisition of microsatellite instability in a clonal model of human T lymphocyte aging. ". Rejuvenation Res. 2008. PMID 18484899.
• "Lynch syndrome genes.". Fam Cancer. 2005. PMID 16136382.