PLEK2

PLEK2
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1X1G
Dynodwyr
Cyfenwau	PLEK2, pleckstrin 2
Dynodwyr allanol	OMIM: 608007 HomoloGene: 8447 GeneCards: PLEK2
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • phosphatidylinositol-3,4-bisphosphate binding • phosphatidylinositol-3,5-bisphosphate binding • phosphatidylinositol-3-phosphate binding Cydrannau o'r gell • cytoplasm • Cellbilen • cell projection • lamellipodium membrane • Cytosgerbwd • bilen Prosesau biolegol • GO:0007243 intracellular signal transduction • actin cytoskeleton organization • positive regulation of cell projection organization • actin cytoskeleton reorganization • positive regulation of plasma membrane bounded cell projection assembly Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	26499	n/a
Ensembl	ENSG00000100558	n/a
UniProt	Q9NYT0	n/a
RefSeq (mRNA)	NM_016445	n/a
RefSeq (protein)	NP_057529	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn PLEK2 yw PLEK2 a elwir hefyd yn Pleckstrin 2 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 14, band 14q23.3-q24.1.

Llyfryddiaeth

• "Cloning, expression and chromosomal assignment of human pleckstrin 2. ". Mol Biol Rep. 2005. PMID 15865208.
• "PI3K regulates pleckstrin-2 in T-cell cytoskeletal reorganization. ". Blood. 2007. PMID 17008542.
• "Pleckstrin homology domains and the cytoskeleton. ". FEBS Lett. 2002. PMID 11911883.
• "Transcriptome profiling of whole blood cells identifies PLEK2 and C1QB in human melanoma. ". PLoS One. 2011. PMID 21698244.
• "Pleckstrin-2 selectively interacts with phosphatidylinositol 3-kinase lipid products and regulates actin organization and cell spreading.". Biochem Biophys Res Commun. 2007. PMID 17658464.