PIR

PIR
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 4ERO, 4EWD, 4GUL, 1J1L, 4EWA, 4HLT, 3ACL, 4EWE
Dynodwyr
Cyfenwau	PIR, pirin
Dynodwyr allanol	OMIM: 300931 HomoloGene: 2717 GeneCards: PIR
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • oxidoreductase activity • GO:0001948, GO:0016582 protein binding • GO:0001104 transcription coregulator activity • dioxygenase activity • metal ion binding • quercetin 2,3-dioxygenase activity Cydrannau o'r gell • cytoplasm • cnewyllyn cell • cytosol • nucleoplasm Prosesau biolegol • myeloid cell differentiation • GO:0009373 regulation of transcription, DNA-templated • monocyte differentiation • transcription by RNA polymerase II • transcription, DNA-templated • Treulio bwyd • regulation of nucleic acid-templated transcription Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	8544	n/a
Ensembl	ENSG00000087842	n/a
UniProt	O00625	n/a
RefSeq (mRNA)	NM_003662 NM_001018109	n/a
RefSeq (protein)	NP_001018119 NP_003653	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn PIR yw PIR a elwir hefyd yn Pirin (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom X dynol, band Xp22.2.

Llyfryddiaeth

• "Sex-specific effect of Pirin gene on bone mineral density in a cohort of 4000 Chinese. ". Bone. 2010. PMID 19766747.
• "Purification, crystallization and preliminary X-ray analysis of human pirin. ". Acta Crystallogr D Biol Crystallogr. 2003. PMID 12876364.
• "Pirin regulates epithelial to mesenchymal transition independently of Bcl3-Slug signaling. ". FEBS Lett. 2015. PMID 25680527.
• "Pirin down-regulates the EAF2/U19 protein and alleviates its growth inhibition in prostate cancer cells. ". Prostate. 2014. PMID 24272884.
• "Pirin inhibits cellular senescence in melanocytic cells.". Am J Pathol. 2011. PMID 21514450.