PIP

PIP
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 3ES6
Dynodwyr
Cyfenwau	PIP, GCDFP-15, GCDFP15, GPIP4, Prolactin-induced protein, prolactin induced protein, BRST-2
Dynodwyr allanol	OMIM: 176720 HomoloGene: 1990 GeneCards: PIP
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • actin binding • GO:0001948, GO:0016582 protein binding • protein dimerization activity • IgG binding • aspartic-type endopeptidase activity Cydrannau o'r gell • extracellular region • apical plasma membrane • extracellular exosome • cnewyllyn cell • extracellular space Prosesau biolegol • negative regulation of T cell apoptotic process • regulation of immune system process • retina homeostasis • GO:1901313 positive regulation of gene expression • detection of chemical stimulus involved in sensory perception of bitter taste • transmembrane transport • proteolysis Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	5304	n/a
Ensembl	ENSG00000159763	n/a
UniProt	P12273	n/a
RefSeq (mRNA)	NM_002652	n/a
RefSeq (protein)	NP_002643	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn PIP yw PIP a elwir hefyd yn Prolactin induced protein (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 7, band 7q34.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn PIP.

• GPIP4
• GCDFP15
• GCDFP-15

Llyfryddiaeth

• "Gross cystic disease fluid protein-15/prolactin-inducible protein as a biomarker for keratoconus disease. ". PLoS One. 2014. PMID 25405607.
• "Gross cystic disease fluid protein 15 (GCDFP-15) expression in breast cancer subtypes. ". BMC Cancer. 2014. PMID 25070172.
• "Prolactin-Induced Protein regulates cell adhesion in breast cancer. ". Biochem Biophys Res Commun. 2015. PMID 26585492.
• "Gross cystic disease fluid protein 15 in stratum corneum is a potential marker of decreased eccrine sweating for atopic dermatitis. ". PLoS One. 2015. PMID 25919462.
• "Prolactin-induced protein in breast cancer.". Adv Exp Med Biol. 2015. PMID 25472539.