PHF21A

PHF21A
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2PUY, 2YQL
Dynodwyr
Cyfenwau	PHF21A, BHC80, BM-006, PHD finger protein 21A, NEDMS, IDDBCS
Dynodwyr allanol	OMIM: 608325 HomoloGene: 9597 GeneCards: PHF21A
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • DNA binding • GO:0031493 histone binding • RNA polymerase II transcription regulatory region sequence-specific DNA binding • chromatin binding • GO:0001104 transcription coregulator activity • GO:0001948, GO:0016582 protein binding • metal ion binding • histone deacetylase activity Cydrannau o'r gell • histone deacetylase complex • DNA repair complex • cnewyllyn cell • nucleoplasm Prosesau biolegol • blood coagulation • GO:1901227 negative regulation of transcription by RNA polymerase II • transcription, DNA-templated • histone deacetylation • GO:0009373 regulation of transcription, DNA-templated • GO:0031497, GO:0006336, GO:0034724, GO:0001301, GO:0007580, GO:0034652, GO:0010847 chromatin organization Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	51317	n/a
Ensembl	ENSG00000135365	n/a
UniProt	Q96BD5	n/a
RefSeq (mRNA)	NM_001101802 NM_016621 NM_001352025 NM_001352026 NM_001352027 NM_001352028 NM_001352029 NM_001352030 NM_001352031 NM_001352032	n/a
RefSeq (protein)	NP_001095272 NP_057705 NP_001338954 NP_001338955 NP_001338956 NP_001338957 NP_001338958 NP_001338959 NP_001338960 NP_001338961	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn PHF21A yw PHF21A a elwir hefyd yn PHD finger protein 21A (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 11, band 11p11.2.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn PHF21A.

• BHC80
• BM-006

Llyfryddiaeth

• "Recognition of unmethylated histone H3 lysine 4 links BHC80 to LSD1-mediated gene repression. ". Nature. 2007. PMID 17687328.
• "Translocations disrupting PHF21A in the Potocki-Shaffer-syndrome region are associated with intellectual disability and craniofacial anomalies. ". Am J Hum Genet. 2012. PMID 22770980.
• "Potocki-Shaffer syndrome in a child without intellectual disability-The role of PHF21A in cognitive function. ". Am J Med Genet A. 2017. PMID 28127865.
• "Gene function in early mouse embryonic stem cell differentiation. ". BMC Genomics. 2007. PMID 17394647.
• "The rest repression of the neurosecretory phenotype is negatively modulated by BHC80, a protein of the BRAF/HDAC complex.". J Neurosci. 2009. PMID 19439607.