PEX19

PEX19
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2W85, 2WL8, 3AJB, 3MK4
Dynodwyr
Cyfenwau	PEX19, D1S2223E, HK33, PBD12A, PMP1, PMPI, PXF, PXMP1, peroxisomal biogenesis factor 19
Dynodwyr allanol	OMIM: 600279 HomoloGene: 134253 GeneCards: PEX19
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • peroxisome membrane class-1 targeting sequence binding • protein N-terminus binding • ATPase binding • GO:0001948, GO:0016582 protein binding Cydrannau o'r gell • cytoplasm • integral component of membrane • cytosol • bilen • peroxisomal membrane • peroxisome • nucleoplasm • brush border membrane • cnewyllyn cell • GO:0009327 protein-containing complex Prosesau biolegol • protein targeting to peroxisome • peroxisome organization • protein stabilization • peroxisome membrane biogenesis • peroxisome fission • protein import into peroxisome membrane • transmembrane transport • establishment of protein localization to peroxisome • negative regulation of lipid binding • chaperone-mediated protein folding Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	5824	n/a
Ensembl	ENSG00000162735	n/a
UniProt	P40855	n/a
RefSeq (mRNA)	NM_001131039 NM_001193644 NM_002857	n/a
RefSeq (protein)	NP_001180573 NP_002848	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn PEX19 yw PEX19 a elwir hefyd yn Peroxisomal biogenesis factor 19 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 1, band 1q23.2.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn PEX19.

• PXF
• HK33
• PMP1
• PMPI
• PXMP1
• PBD12A
• D1S2223E

Llyfryddiaeth

• "The import competence of a peroxisomal membrane protein is determined by Pex19p before the docking step. ". J Biol Chem. 2006. PMID 16980692.
• "Functional domains and dynamic assembly of the peroxin Pex14p, the entry site of matrix proteins. ". J Biol Chem. 2006. PMID 16459329.
• "A mutation in PEX19 causes a severe clinical phenotype in a patient with peroxisomal biogenesis disorder. ". Am J Med Genet A. 2010. PMID 20683989.
• "Elevated delta-6 desaturase (FADS2) expression in the postmortem prefrontal cortex of schizophrenic patients: relationship with fatty acid composition. ". Schizophr Res. 2009. PMID 19195843.
• "Import of peroxisomal membrane proteins: the interplay of Pex3p- and Pex19p-mediated interactions.". Biochim Biophys Acta. 2006. PMID 17069900.