PEBP1

PEBP1
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1BD9, 1BEH, 2L7W, 2QYQ
Dynodwyr
Cyfenwau	PEBP1, HCNP, HCNPpp, HEL-210, HEL-S-34, PBP, PEBP, PEBP-1, RKIP, HEL-S-96, Phosphatidylethanolamine binding protein 1
Dynodwyr allanol	OMIM: 604591 HomoloGene: 37637 GeneCards: PEBP1
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • GO:0001948, GO:0016582 protein binding • lipid binding • nucleotide binding • protein kinase binding • phosphatidylethanolamine binding • serine-type endopeptidase inhibitor activity • ATP binding • enzyme binding • peptidase inhibitor activity • RNA binding • signaling receptor binding • mitogen-activated protein kinase binding Cydrannau o'r gell • cytoplasm • cytosol • cnewyllyn cell • extracellular exosome • extracellular space • mitocondria • mitochondrial outer membrane • Golgi apparatus • synaptic vesicle • cell surface • soma • myelin sheath • axon terminus • apical part of cell Prosesau biolegol • MAPK cascade • negative regulation of peptidase activity • negative regulation of endopeptidase activity • regulation of neurotransmitter levels • regulation of the force of heart contraction • GO:0001306 response to oxidative stress • GO:0010260 heneiddio • response to heat • response to wounding • response to toxic substance • response to organonitrogen compound • response to activity • hippocampus development • negative regulation of MAPK cascade • positive regulation of cAMP-mediated signaling • response to ethanol • positive regulation of mitotic nuclear division • sperm capacitation • response to corticosterone • response to cAMP • response to calcium ion • positive regulation of acetylcholine metabolic process Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	5037	n/a
Ensembl	ENSG00000089220	n/a
UniProt	P30086	n/a
RefSeq (mRNA)	NM_002567	n/a
RefSeq (protein)	NP_002558	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn PEBP1 yw PEBP1 a elwir hefyd yn Phosphatidylethanolamine binding protein 1 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 12, band 12q24.23.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn PEBP1.

• PBP
• HCNP
• PEBP
• RKIP
• HCNPpp
• PEBP-1
• HEL-210
• HEL-S-34
• HEL-S-96

Llyfryddiaeth

• "PEBP1 Wardens Ferroptosis by Enabling Lipoxygenase Generation of Lipid Death Signals. ". Cell. 2017. PMID 29053969.
• "[Knockdown of Raf kinase inhibitor protein promotes the proliferation of LX-2 human hepatic stellate cells]. ". Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi. 2017. PMID 28031115.
• "Prognostic value of phosphorylated Raf kinase inhibitory protein at serine 153 and its predictive effect on the clinical response to radiotherapy in nasopharyngeal carcinoma. ". Radiat Oncol. 2016. PMID 27647315.
• "Locostatin, a disrupter of Raf kinase inhibitor protein, inhibits extracellular matrix production, proliferation, and migration in human uterine leiomyoma and myometrial cells. ". Fertil Steril. 2016. PMID 27565262.
• "Effects of Raf kinase inhibitor protein expression on pancreatic cancer cell growth and motility: an in vivo and in vitro study.". J Cancer Res Clin Oncol. 2016. PMID 27444299.